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A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm
ArticleAbstract: Background: Intrabodies are defined as antibody molecules which are ectopically expressed inside thePalabras claves:Autores:Bec N., Christian Larroque, Courtête J., Martineau P., Philibert P., Saven J.G., Sibler A.P., Stoessel A., Wang W., Weiss E.Fuentes:scopusCyclophilin A as negative regulator of apoptosis by sequestering cytochrome c
ArticleAbstract: The release of cytochrome c from the mitochondrial intermembrane space is a decisive event in prograPalabras claves:apoptosis, BRAIN, Cyclophilin A, Cytochrome c, Phosphatidylethanolamine-binding protein, Procaspase-3, TumorAutores:Bec N., Bonfils C., Christian Larroque, Gongora C., Martineau P., Pugniere M., Rio M.D.Fuentes:scopusFANCD2 Binds MCM Proteins and Controls Replisome Function upon Activation of S Phase Checkpoint Signaling
ArticleAbstract: Proteins disabled in Fanconi anemia (FA) are necessary for the maintenance of genome stability durinPalabras claves:Autores:Bec N., Christian Larroque, Constantinou A., Décaillet C., Gari K., Larroque M., Lossaint G., Ribeyre C.Fuentes:scopusDifferential Effect of Curcumin on the Nanomechanics of Normal and Cancerous Mammalian Epithelial Cells
ArticleAbstract: Though the pharmacological activity of curcumin inhibiting the proliferation of certain cancer cellsPalabras claves:atomic force microscopy, curcumin, Elasticity measurements, Fluorescence, HMEC, Mammalian cells, MCF7Autores:Bec N., Christian Larroque, Cuisinier F.J.G., Estephan E., Gergely C., Martin M., Saab M.B.Fuentes:scopusNascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks
ArticleAbstract: During transcription and DNA replication, the DNA template is overwound ahead of RNA and DNA polymerPalabras claves:Autores:Bec N., Chauvin M., Christian Larroque, Constantinou A., Lopes M., Ribeyre C., Zellweger R.Fuentes:scopusImidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity
ArticleAbstract: Displaying a strong antiproliferative activity on a wide variety of cancer cells, EAPB0203 and EAPB0Palabras claves:Autores:Bec N., Christian Larroque, Constant C., Courbet A., Deleuze-Masquéfa C., Gattacceca F., Khier S., Messaoudi S.E., Pugniere M., Zghaib Z.Fuentes:scopusPhytochemical and ethnomedicinal study of Huperzia species used in the traditional medicine of Saraguros in Southern Ecuador; AChE and MAO inhibitory activity
ArticleAbstract: Ethnobotanical and ethnomedicinal relevance This study concerns seven Huperzia species (LycopodiaceaPalabras claves:AChE and MAO-A inhibitory activity, alkaloids, ALZHÉIMER, Hallucinogenic, Huperzia, phytochemistry, Saraguro traditional medicine, Southern Ecuador, Traditional medicine of EcuadorAutores:Bec N., Bracco F., C. Armijos Riofrio, C. Larroque, Chabaco Armijos Riofrio, Christian Larroque, F. Bracco, Finzi P.V., G Gilardoni, G. Vidari, Gianluca Gilardoni, J. Ramirez Robles, Jorge Ramirez, L. Amay, Lozano A., Luis Amay, M. Lozano, N. Bec, P. Vita Finzi, Vidari G.Fuentes:googlerraaescopusKinetic analysis of tubulin assembly in the presence of the microtubule-associated protein TOGp
ArticleAbstract: The microtubule-associated protein TOGp, which belongs to a widely distributed protein family from yPalabras claves:Autores:Bec N., Bonfils C., Christian Larroque, Harricane M.C., Lacroix B.Fuentes:scopusSelection for intrabody solubility in mammalian cells using GFP fusions
ArticleAbstract: Single-chain antibody fragments (scFv) expressed in the cytoplasm of mammalian cells, also called inPalabras claves:aggregation, Degradation, folding, GFP, intrabodyAutores:Bec N., Christian Larroque, Dariavach P., Denis V., Guglielmi L., Martineau P., Vezzio-Vié N.Fuentes:scopusSelective BuChE inhibitory activity, chemical composition, and enantiomer content of the volatile oil from the Ecuadorian plant Clinopodium brownei
ArticleAbstract: This paper describes the chemical composition and the enantiomer content of the volatile oil hydrodiPalabras claves:Clinopodium brownei, Enantioselective GC-MS, in vitro BuChE inhibitory activity, Lamiaceae, Volatile oilAutores:Andrea Matailo, Bec N., Chabaco Armijos Riofrio, Christian Larroque, James Calva, James Willan Calva, Jorge Ramirez, José Miguel Andrade, Vidari G.Fuentes:googlescopus