Mostrando 4 resultados de: 4
Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes
ArticleAbstract: Background: Losartan is metabolized to losartan carboxylic acid (E-3174) by the polymorphic cytochroPalabras claves:CYP2C9*Hispanics, LOSARTÁN, pharmacogenetics, PhenotypeAutores:Adrián LLerena, de Andrés F., Dorado P., Machín E., Naranjo M.E.G., Penãs-Lledó E.M.Fuentes:scopusCYP2D6 genotype and dextromethorphan hydroxylation phenotype in an Ecuadorian population
ArticleAbstract: Purpose: Cytochrome P450 2D6 (CYP2D6) genotypes and the dextromethorphan/dextrorphan (DXM/DXT) metabPalabras claves:CYP2D6, dextromethorphan, ECUADOR, pharmacogeneticsAutores:Adrián LLerena, Dorado P., Enrique Terán, Francisco J.López Hernández, Machín E., Natalia HerasFuentes:scopusLosartan hydroxylation phenotype in an Ecuadorian population: Influence of CYP2C9 genetic polymorphism, habits and gender
ArticleAbstract: Aim: To describe for the first time CYP2C9 hydroxylation phenotype with CYP2C9 genotypes in a HispanPalabras claves:CYP2C9 genotype, CYP2C9 hydroxylation, Ecuadorians, Hispanics, LOSARTÁNAutores:Adrián LLerena, Dorado P., Enrique Terán, Leonardo J. Beltrán, Machín E., Penãs-Lledó E.M.Fuentes:scopusPharmacogenetics of the antiepileptic drugs phenytoin and lamotrigine
ReviewAbstract: Patients treated with antiepileptic drugs can exhibit large interindividual variability in clinicalPalabras claves:antiepileptic drug, Cytochrome p450, lamotrigine, pharmacogenetics, Phenytoin, UDP-glucuronosyltransferase (UGT)Autores:Adrián LLerena, Dorado P., ElisaAlonso M., Jung-Cook H., López M.L., Machín E., MELANIE BRIGETTE ARROYO LOPEZ, Monroy-Jaramillo N., Penãs-Lledó E.M.Fuentes:googlescopus