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Molecular Neurobiology(4)
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scopus(21)
C-Jun N-Terminal Kinases in Alzheimer's Disease: A Possible Target for the Modulation of the Earliest Alterations
ReviewAbstract: Given the highly multifactorial origin of Alzheimer's disease (AD) neuropathology, disentangling andPalabras claves:Alzheimer's disease, Amyloid-β, axonal transport, hyperphosphorylated tau, JNK, synapse lossAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusA metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
ReviewAbstract: Alzheimer's disease (AD) represents a global burden in the economics of healthcare systems. Amyloid-Palabras claves:ADAM10, Alzheimer's disease, Natural compounds, Pharmaceutical, α-SecretaseAutores:Antoni Camins, Busquets O., Cano A., Cominetti M.R., Di Luca M., Endres K., Ettcheto M., Manzine P.R., Marcello E., Olloquequi J., Pelucchi S.Fuentes:scopusDexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice
ArticleAbstract: Background: Several studies stablished a relationship between metabolic disturbances and Alzheimer´sPalabras claves:Alzheimer´s disease, APPswe/PS1dE9, Cognitive deficits, Dexibuprofen, High fat diet, Metabolic alterations, neuroinflammation, synapsis, unfolded protein response, βA plaquesAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Carrasco M., Espinosa-Jimenez T., Ettcheto M., Folch J., Herrera K., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusCorrigendum to “Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6 J mice. A potential model of sporadic Alzheimer's disease” [J. Mech. Ageing Dev. 162 (March) (2017) 38-45](S0047637416300859)(10.1016/j.mad.2016.11.002)
OtherAbstract: The authors regret that there are some errors in the original Figures 2, 3 and 5. A reader brought tPalabras claves:Autores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusGSPE pre-treatment protects against long-term cafeteria diet-induced mitochondrial and inflammatory affectations in the hippocampus of rats
ArticleAbstract: Deregulations like the loss of sensitivity to insulin (insulin resistance) and chronic inflammationPalabras claves:BRAIN, Cafeteria, diet, GSPE, hippocampus, inflammation, metabolism, StressAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Carrasco M., Espinosa-Jimenez T., Ettcheto M., Folch J., Pinent M., Rodríguez-Gallego E., Verdaguer E.Fuentes:scopusEpigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet Through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice
ArticleAbstract: Epigallocatechin-3-gallate (EGCG), a catechin found in green tea, has been previously investigated fPalabras claves:APPswe/PS1dE9 mice, Cognitive deficits, Epigallocatechin-3-gallate, hippocampus, obesity, unfolded protein responseAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Verdaguer E., Zárate C.B.Fuentes:scopusExperimental models for aging and their potential for novel drug discovery
ReviewAbstract: Background: An interesting area of scientific research is the development of potential antiaging druPalabras claves:aging, Heterogeneous mice model, IGF-1, mTOR, Resveratrol, SAMP8, SirtuinsAutores:Antoni Camins, Auladell C., Busquets O., Casadesús G., Ettcheto M., Folch J., Miguel Marin, Olloquequi J., Pallás M., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusPeripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease
ArticleAbstract: There is growing evidence that obesity associated with type 2 diabetes mellitus (T2DM) and aging arePalabras claves:Alzheimer’s disease, APPswe/PS1dE9, DIABÉTES, high-fat diet, Memantine, obesityAutores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Vázquez-Carrera M., Zárate C.B.Fuentes:scopus