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Journal of Alzheimer's Disease(2)
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A chronological review of potential disease-modifying therapeutic strategies for Alzheimer's disease
ReviewAbstract: Late-onset Alzheimer’s disease (LOAD) is a neurodegenerative disorder that has become a worldwide hePalabras claves:Alzheimer’s disease, calcium, ER stress, glutamate, Neurodegeneration, neuroinflammation, Oxidative Stress, Parkinson’s DiseaseAutores:Antoni Camins, Auladell C., Busquets O., Espinosa-Jimenez T., Ettcheto M., Verdaguer E.Fuentes:scopusA metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusDexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice
ArticleAbstract: Background: Several studies stablished a relationship between metabolic disturbances and Alzheimer´sPalabras claves:Alzheimer´s disease, APPswe/PS1dE9, Cognitive deficits, Dexibuprofen, High fat diet, Metabolic alterations, neuroinflammation, synapsis, unfolded protein response, βA plaquesAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Carrasco M., Espinosa-Jimenez T., Ettcheto M., Folch J., Herrera K., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusPeroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations
ArticleAbstract: Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), the most PPAR abundant isotype in the centPalabras claves:dendritic spines, high-fat diet, insulin signaling, Memory impairment, neuroinflammation, PPARβ/δ, synapsis, T2DMAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Espinosa-Jimenez T., Ettcheto M., Folch J., Olloquequi J., Parcerisas A., Sanchez-Lopez E., Vázquez-Carrera M., Verdaguer E., Wahli W.Fuentes:scopusPharmacological Strategies to Improve Dendritic Spines in Alzheimer's Disease
ReviewAbstract: To deeply understand late onset Alzheimer's disease (LOAD), it may be necessary to change the concepPalabras claves:BDNF, dendritic spines, late onset Alzheimer's disease, neuroinflammation, obesity, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Casadesús G., Castro-Torres R.D., Espinosa-Jimenez T., Ettcheto M., Folch J., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Sureda F.X., Verdaguer E.Fuentes:scopusRole of brain c-Jun N-terminal kinase 2 in the control of the insulin receptor and its relationship with cognitive performance in a high-fat diet pre-clinical model
ArticleAbstract: Insulin resistance has negative consequences on the physiological functioning of the nervous system.Palabras claves:ER stress, high-fat diet, JNK, metabolism, neuroinflammation, PTP1BAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Eritja À., Ettcheto M., Folch J., López B.M., Manzine P.R., Olloquequi J., Vázquez-Carrera M., Verdaguer E.Fuentes:scopusPotential preventive disease-modifying pharmacological strategies to delay late onset Alzheimer's disease
ReviewAbstract: Alzheimer's disease (AD) is a progressive neurodegenerative disease that was histopathologically chaPalabras claves:Alzheimer's disease, amyloid, Beta-secretase, glutamate, N-methyl-D-aspartate, neuroinflammation, TauAutores:Antoni Camins, Busquets O., Ettcheto M.Fuentes:scopusThe Ethyl Acetate Extract of Leaves of Ugni molinae Turcz. Improves Neuropathological Hallmarks of Alzheimer's Disease in Female APPswe/PS1dE9 Mice Fed with a High Fat Diet
ArticleAbstract: The most common type of dementia is Alzheimer's disease (AD), a progressive neurodegenerative diseasPalabras claves:APPswe/PS1dE9, ethyl acetate extract, High fat diet, hippocampus, neuroinflammation, Ugni molinaeAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Delporte C., Ettcheto M., Folch J., Jara-Moreno D., Kogan M.J., Verdaguer E.Fuentes:scopus