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A metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusAnti-inflammatory role of Leptin in glial cells through p38 MAPK pathway inhibition
ArticleAbstract: Background In the present work, we studied the modulatory effect of Leptin (Lep) against pro-inflammPalabras claves:Caspase-3, Cytochrome-c, Glial cells, iNOS, leptin, p38 MAPKAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Martí A., Martínez N., Miguel Marin, Patraca I., Pedros I., Sureda F.X., Zárate C.B.Fuentes:scopusCorrection to: Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease (Molecular Neurobiology, (2018), 55, 9, (7327-7339), 10.1007/s12035-018-0868-4)
OtherAbstract: The original version of this article unfortunately contained mistake. The authors found that Fig. 4.Palabras claves:Autores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carrera M.V., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusCorrigendum to “Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6 J mice. A potential model of sporadic Alzheimer's disease” [J. Mech. Ageing Dev. 162 (March) (2017) 38-45](S0047637416300859)(10.1016/j.mad.2016.11.002)
OtherAbstract: The authors regret that there are some errors in the original Figures 2, 3 and 5. A reader brought tPalabras claves:Autores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusDexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice
ArticleAbstract: Background: Several studies stablished a relationship between metabolic disturbances and Alzheimer´sPalabras claves:Alzheimer´s disease, APPswe/PS1dE9, Cognitive deficits, Dexibuprofen, High fat diet, Metabolic alterations, neuroinflammation, synapsis, unfolded protein response, βA plaquesAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Carrasco M., Espinosa-Jimenez T., Ettcheto M., Folch J., Herrera K., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusGSPE pre-treatment protects against long-term cafeteria diet-induced mitochondrial and inflammatory affectations in the hippocampus of rats
ArticleAbstract: Deregulations like the loss of sensitivity to insulin (insulin resistance) and chronic inflammationPalabras claves:BRAIN, Cafeteria, diet, GSPE, hippocampus, inflammation, metabolism, StressAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Carrasco M., Espinosa-Jimenez T., Ettcheto M., Folch J., Pinent M., Rodríguez-Gallego E., Verdaguer E.Fuentes:scopusEpigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet Through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice
ArticleAbstract: Epigallocatechin-3-gallate (EGCG), a catechin found in green tea, has been previously investigated fPalabras claves:APPswe/PS1dE9 mice, Cognitive deficits, Epigallocatechin-3-gallate, hippocampus, obesity, unfolded protein responseAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Verdaguer E., Zárate C.B.Fuentes:scopusJNK1 and JNK3: divergent functions in hippocampal metabolic-cognitive function
ArticleAbstract: Background and aim: The appearance of alterations in normal metabolic activity has been increasinglyPalabras claves:COGNITION, high-fat diet, JNK1, JNK3, metabolismAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cantero J.L., Carro E., Casadesús G., Espinosa-Jimenez T., Ettcheto M., Folch J., Olloquequi J., Verdaguer E.Fuentes:scopusThe Ethyl Acetate Extract of Leaves of Ugni molinae Turcz. Improves Neuropathological Hallmarks of Alzheimer's Disease in Female APPswe/PS1dE9 Mice Fed with a High Fat Diet
ArticleAbstract: The most common type of dementia is Alzheimer's disease (AD), a progressive neurodegenerative diseasPalabras claves:APPswe/PS1dE9, ethyl acetate extract, High fat diet, hippocampus, neuroinflammation, Ugni molinaeAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Delporte C., Ettcheto M., Folch J., Jara-Moreno D., Kogan M.J., Verdaguer E.Fuentes:scopusThe Involvement of Peripheral and Brain Insulin Resistance in Late Onset Alzheimer’s Dementia
ReviewAbstract: Nowadays, Alzheimer’s disease (AD) is a severe sociological and clinical problem. Since it was firstPalabras claves:Alzheimer’s disease, Insulin Resistance, Mediterranean diet, neuroinflammation and neurodegeneration, obesity, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cano A., Casadesús G., Espinosa-Jimenez T., Ettcheto M., Folch J., García M.L., Olloquequi J., Sanchez-Lopez E., Zárate C.B.Fuentes:scopus