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C-Jun N-Terminal Kinases in Alzheimer's Disease: A Possible Target for the Modulation of the Earliest Alterations
ReviewAbstract: Given the highly multifactorial origin of Alzheimer's disease (AD) neuropathology, disentangling andPalabras claves:Alzheimer's disease, Amyloid-β, axonal transport, hyperphosphorylated tau, JNK, synapse lossAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusDexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice
ArticleAbstract: Background: Several studies stablished a relationship between metabolic disturbances and Alzheimer´sPalabras claves:Alzheimer´s disease, APPswe/PS1dE9, Cognitive deficits, Dexibuprofen, High fat diet, Metabolic alterations, neuroinflammation, synapsis, unfolded protein response, βA plaquesAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Carrasco M., Espinosa-Jimenez T., Ettcheto M., Folch J., Herrera K., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusPharmacological Strategies to Improve Dendritic Spines in Alzheimer's Disease
ReviewAbstract: To deeply understand late onset Alzheimer's disease (LOAD), it may be necessary to change the concepPalabras claves:BDNF, dendritic spines, late onset Alzheimer's disease, neuroinflammation, obesity, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Casadesús G., Castro-Torres R.D., Espinosa-Jimenez T., Ettcheto M., Folch J., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Sureda F.X., Verdaguer E.Fuentes:scopus