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Impact of regional variation in Bothrops asper snake venom on the design of antivenoms: Integrating antivenomics and neutralization approaches
ArticleAbstract: Intraspecific snake venom variations have implications in the preparation of venom pools for the genPalabras claves:antivenom, Antivenomics, Bothrops asper, Phospholipase A 2, Snake venom metalloproteinase, Snake venom proteome, Venom neutralization assays, venomicsAutores:Adolfo Borges, Alape-Girón A., Calvete J.J., Estrada R., Figueroa L., Flores-Díaz M., Gutiérrez J.M., Herrera M., León G., Madrigal M., Sanz L., Villalta M.Fuentes:scopusSnake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management
ArticleAbstract: We describe two geographically differentiated venom phenotypes across the wide distribution range ofPalabras claves:BOTHROPS ATROX, Geographic venom variability, Mass spectrometry, N-terminal sequence, Paedomorpohism, Snake population venomics, Snake venom proteomicsAutores:Adolfo Borges, Angulo Y., Calvete J.J., Chalkidis H.M., Furtado M.F.D., Gutiérrez J.M., Lomonte B., Moura-Da-Silva A.M., Mourão R.H.V., Pérez A., Sanz L., Vargas A.M.Fuentes:scopusSnake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing to its taxonomy and snakebite management
ArticleAbstract: The taxonomic status of the medically important pitviper of the Bothrops atrox-asper complex endemicPalabras claves:Antibothropic and anticrotalic ABC antivenom, Antivenomics, Bothrops colombiensis, Mass spectrometry, N-terminal sequencing, Polyvalent (crotalinae) ICP antivenom, proteomics, Snake venom protein families, Snake venomics, Viperid toxinsAutores:Adolfo Borges, Alape-Girón A., Calvete J.J., De Sousa L., Escolano J., Faks J.G., Flores-Díaz M., Gutiérrez J.M., Kiriakos D., Nardy Diez, Sánchez E., Sanz L., Segura A.Fuentes:googlescopusSnake venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal in South America
ArticleAbstract: We report a comparative venomic and antivenomic characterization of the venoms of newborn and adultPalabras claves:Antibothropic and anticrotalic ABC antivenom, Antivenomics, Crotalus durissus, Crotalus simus, Crotoxin, Ontogenetic shift, Paedomorphism, Polyvalent (crotalinae) ICP antivenom, Snake venom protein families, Snake venomicsAutores:Adolfo Borges, Alape-Girón A., Angulo Y., Bremo A., Calvete J.J., Cid P., De La Torre P., Dos-Santos M.C., Flores-Díaz M., Gutiérrez J.M., Lomonte B., Sanz L.Fuentes:scopusSystemic cytokine response in children bitten by snakes in Costa Rica
ArticleAbstract: Background: To characterize the host response to venom from snakes of the family Viperidae in CostaPalabras claves:cytokines, Inflammatory, Snakebites, Systemic response, VIPERIDAEAutores:Faingezicht I., Gutiérrez J.M., Hu S., Lomonte B., Maria L. Avila-Aguero, Paris M.M., Peterson P.K.Fuentes:scopus