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Clinical and Translational Science(1)
Frontiers in Genetics(1)
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International Journal of Obesity(1)
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Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes
ArticleAbstract: Background/objectives: Admixed populations are a resource to study the global genetic architecture oPalabras claves:Autores:Alvim I.O., Araujo G.S., Araújo N.M., Borda V., Choudhury A., Duarte Y.A.O., Dutil J., Gilman R.H., Gouveia M.H., Guio H., Hansen M.E.B., Horta B.L., Hsing A.W., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Lobo F., Luizon M.R., Lyra R., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Mbulaiteye S.M., Mensah J., Michelin L.A., Naslavsky M.S., Norris S.A., O´Connor T.D., Passos-Bueno M.R., Peixoto S.V., Pereira A.C., Ramsay M., Rodrigues M.R., Santolalla M.L., Sant’Anna H.P., Scliar M.O., Tarazona-Santos E.M., Tishkoff S.A., Yamamoto G.L., Yeager M., Yeboah E., Zatz M., Zolini C.Fuentes:scopusGenomic ancestry, Self-rated health and its association with mortality in an admixed population: 10 year follow-up of the Bambui-Epigen (Brazil) cohort study of ageing
ArticleAbstract: Background: Self-rated health (SRH) has strong pbkp_redictive value for mortality in different contePalabras claves:Autores:Castro-Costa E., Cesar C.C., Firmo J.O.A., Horta B.L., Leal T.P., Lima-Costa M.F., Macinko J., Magalhães W.C.S., Mauricio L. Barreto, Peixoto S.V., Pereira A.C., Proietti F.A., Rodrigues M.R., Tarazona-Santos E.M., Vaz De Melo Mambrini J.Fuentes:scopusEPIGEN-Brazil Initiative resources: A Latin American imputation panel and the Scientific Workflow
ArticleAbstract: EPIGEN-Brazil is one of the largest Latin American initiatives at the interface of human genomics, pPalabras claves:Autores:Alvim I.O., Araujo G.S., Araújo N.M., Borda V., Costa G.N.O., Gouveia M.H., Horta B.L., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Moreira R.G., Pereira A.C., Rodrigues M.R., Rodrigues-Soares F., Sant Anna H.P., Santolalla M.L., Scliar M.O., Soares-Souza G.B., Tarazona-Santos E.M., Viriato P.J.S., Zamudio R., Zolini C.Fuentes:scopusOrigin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations
ArticleAbstract: While South Americans are underrepresented in human genomic diversity studies, Brazil has been a claPalabras claves:Bambuí cohort study of ageing, Latin America, Pelotas birth cohort study, Population genetics, Salvador SCAALAAutores:Araujo G.S., Beleza S., Berg D.E., Cabrera L., Costa G.N.O., Debortoli G., Duarte D., Duarte N.E., Fiaccone R.L., Figueiredo C.A.V., Ghirotto S., Gilman R.H., Gonçalves V.F., Gouveia M.H., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Machado M., Magalhães W.C.S., Marrero A.R., Mauricio L. Barreto, Moreira R.G., Muniz Y.C., Pereira A.C., Rodrigues L.C., Rodrigues M.R., Rodrigues-Soares F., Sant Anna H.P., Santos H.C., Scliar M.O., Silva T.M., Soares-Souza G.B., Tarazona-Santos E.M., Weissensteiner H., Yeager M., Zamudio R.Fuentes:scopusOrigins, admixture dynamics, and homogenization of the african gene pool in the americas
ArticleAbstract: The Transatlantic Slave Trade transportedmore than 9 million Africans to the Americas between the eaPalabras claves:Admixture dynamics, African Diaspora, MESTIZAJE, Transatlantic Slave TradeAutores:Alvim I.O., Aquino M.M., Araujo G.S., Araújo N.M., Bergen A.W., Borda V., Catira Bortolini M., Chanock S.J., Dean M., Furlan V., Gilman R.H., Gouveia M.H., Guio H., Horta B.L., Kehdy F.S.G., Leal T.P., Liboredo R., Lima-Costa M.F., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Mbulaiteye S.M., Michelin L.A., Moreira R.G., Pereira A.C., Rocha J., Rodrigues M.R., Rodrigues-Soares F., Sant Anna H.P., Santolalla M.L., Scliar M.O., Soares-Souza G.B., Tarazona-Santos E.M., Tishkoff S.A., Yeager M., Zamudio R., Zolini C.Fuentes:scopusTracing the Distribution of European Lactase Persistence Genotypes Along the Americas
ArticleAbstract: In adulthood, the ability to digest lactose, the main sugar present in milk of mammals, is a phenotyPalabras claves:dairy consumption, lactose intolerance, Latin America, MCM6 gene, nutrition policies, Population genetics, –13910C > TAutores:Adelman Cipolla G., Arboleda G., Arboleda H., Arboleda-Bustos C.E., Beltrame M.H., Borda V., Borges V., Cáceres O., Chana-Cuevas P., Dean M., Dieguez E., Fernandez W., Ferraz H.B., Guimarães Alves A.C., Guio H., Kaplan R., Leal T.P., Lehtonen Rodrigues Souza R., Lescano A.G., Lima-Costa M.F., Loesch D., Machado M., Mata I.F., Mauricio L. Barreto, Mendes M., Moon J.Y., North K.E., O’Connor T.D., Padilla C., Petzl-Erler M.L., Raggio V., Rainha de Souza I., Rieder C.R.M., Sanchez C., Santolalla M.L., Santos-Lobato B.L., Shumacher-Schuh A., Sukow N.M., Tarazona-Santos E.M., Tumas V., Weiss S.T.Fuentes:scopusPopulation genetics of PDE4B (phosphodiesterase-4B) in neglected Native Americans: Implications for cancer pharmacogenetics
ArticleAbstract: PDE4B (phosphodiesterase-4B) has an important role in cancer and in pharmacology of some disorders,Palabras claves:Autores:Adrián LLerena, Balázs Z., Borda V., Galaviz-Hernandez C., Gilman R.H., Guio H., Leal T.P., Magalhães W.C.S., Mill J.G., Moreira R.G., O’Connor T.D., Pereira A.C., Rodrigues-Soares F., Santolalla M.L., Saraiva-Duarte J.M., Sosa-Macías M.G., Tarazona-Santos E.M., Zolini C.Fuentes:scopus