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Bone Morphogenetic Protein-4 (BMP4): A paracrine regulator of human adrenal C<inf>19</inf> steroid synthesis
ArticleAbstract: Bone morphogenetic proteins (BMPs) comprise one of the largest subgroups in the TGF-β ligand superfaPalabras claves:Autores:Nishimoto H.K., Nishimoto K., Rainey W.E., Rege J., Richard J. Auchus, Rodgers R.J.Fuentes:scopusElectrochemistry of cytochrome P450 17α-hydroxylase/17,20-lyase (P450c17)
ReviewAbstract: Within the superfamily of cytochrome P450 enzymes (P450s), there is a small class which is functionaPalabras claves:adrenal cortex, androgen, CYP17A1, Cytochrome P450c17, Direct electrochemistry, electron transfer, mechanism, steroidogenesisAutores:Bond A.M., Conley A.J., Corbin C.J., Kubeil C., Kuznetsov V.L., Martin L.L., Richard J. Auchus, Rodgers R.J., Simonov A.N.Fuentes:scopusMechanistic scrutiny identifies a kinetic role for cytochrome b5 regulation of human cytochrome P450c17 (CYP17A1, P450 17A1)
ArticleAbstract: Cytochrome P450c17 (P450 17A1, CYP17A1) is a critical enzyme in the synthesis of androgens and is noPalabras claves:Autores:Bond A.M., Conley A.J., Corbin C.J., Holien J.K., Kuznetsov V.L., Martin L.L., Nguyen A.D., Parker M.W., Richard J. Auchus, Rodgers R.J., Simonov A.N., Yeung J.C.I., Zheng J.Fuentes:scopus