Mostrando 10 resultados de: 22
Publisher
Enzyme and Microbial Technology(9)
Annals of the New York Academy of Sciences(2)
Biotechnology and Bioengineering(2)
Journal of Molecular Catalysis(2)
Biocatalysis and Biotransformation(1)
Área temáticas
Ingeniería química(10)
Bioquímica(9)
Química analítica(6)
Química orgánica(6)
Farmacología y terapéutica(5)
Origen
scopus(22)
A criterion for the selection of monophasic solvents for enzymatic synthesis
ArticleAbstract: Penicillin acylase can be used for the production of β-lactamic antibiotics which have a wide rangePalabras claves:Antibiotic, Enzyme stability, Equilibrium-controlled synthesis, Organic solvent selection, Penicillin acylaseAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M., Terreni M.Fuentes:scopusAdditional stabilization of penicillin G acylase-agarose derivatives by controlled chemical modification with formaldehyde
ArticleAbstract: We have tested the effect of chemical modifications with formaldehyde on the activity/stability of iPalabras claves:chemical modification of proteins, Enzyme stabilization, formaldehyde treatment of enzymes, immobilization-stabilization of enzymesAutores:Alvaro G., Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusDesign of novel biocatalysts by 'bioimprinting' during unfolding-refolding of fully dispersed covalently immobilized enzymes
Conference ObjectAbstract:Palabras claves:Autores:Blanco R.M., Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M., Soler G.Fuentes:scopusFacile synthesis of artificial enzyme nano-environments via solid-phase chemistry of immobilized derivatives: Dramatic stabilization of penicillin acylase versus organic solvents
ArticleAbstract: A method to generate a highly hydrophilic nano-environment surrounding immobilized enzymes [penicillPalabras claves:Artificial nano-environments, Dextrans, Enzymes in organic media, Immobilized enzymes, Solid-phase modification of proteins, Stabilization of enzymesAutores:Caanan-Haden L., Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M., Rodes L.Fuentes:scopusEnzyme reaction engineering: Synthesis of antibiotics catalysed by stabilized penicillin G acylase in the presence of organic cosolvents
ArticleAbstract: By using very active and very stable penicillin G acylase (PGA)-agarose derivatives we have studiedPalabras claves:antibiotic synthesis by penicillin G acylase, design of thermodynamically controlled synthesis, enzymes in organic solvents, Enzymes in organic synthesisAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusDynamic reaction design of enzymic biotransformations in organic media: Equilibrium-controlled synthesis of antibiotics by penicillin G acylase
ArticleAbstract: Parameters relevant to the thermodynamically controlled synthesis of cephalothin utilizing highly acPalabras claves:Autores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusImmobilization-stabilization of proteases as a tool to improve the industrial design of peptide synthesis
Conference ObjectAbstract: Synthesis of dipeptides benzoyl arginine leucinamide and kyotorphin catalyzed by highly stabilized dPalabras claves:Autores:Alvaro G., Bastida A., Blanco R.M., Cristina M. Rosell, Cuesta C., Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusImmobilization‐stabilization of α‐chymotrypsin by covalent attachment to aldehyde‐agarose gels
ArticleAbstract: We have developed a strategy for immobilization‐stabilization of α‐chymotrypsin by multipoint covalePalabras claves:effect of denaturing agents, enzyme‐support multipoint attachment, stabilization of chymotrypsinAutores:Bastida A., Cristina M. Rosell, Cuesta C., Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusModification of enzyme properties by the use of inhibitors during their stabilisation by multipoint covalent attachment
ArticleAbstract: The effect of a number of inhibitors adsorbed at the active site of penicillin acylase during immobiPalabras claves:inhibitor, Penicillin acylase, StabilisationAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopusModulation of the properties of penicillin G acylase by acyl donor substrates during N-protection of amino compounds
ArticleAbstract: The rates and yields in the synthesis of N-protected amino compounds catalyzed by penicillin G acylaPalabras claves:Enzyme modulation, Enzymes (in fine chemistry), Optically pure compound synthesis, Penicillin G acylase, Protection of amino compoundsAutores:Cristina M. Rosell, Fernandez‐Lafuente R., Guisan J.M.Fuentes:scopus