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Article(3)
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Farmacología y terapéutica(3)
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Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics
ArticleAbstract: We describe the synthesis and binding affinities on D2, 5-HT2A and 5-HT2C receptors of 6-aminomethylPalabras claves:antipsychotics, Butyrophenones, dopamine, Isoxazole, Pyrazole, SerotoninAutores:Barceló M., Brea J., Domínguez E., Filipe Miguel Areias, Loza M.I., Masaguer C.F., Raviña E.Fuentes:googlescopusSynthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D<inf>3</inf> receptor ligands
ArticleAbstract: A series of new benzolactam derivatives was synthesized and the derivatives were evaluated for theirPalabras claves:antipsychotics, Arylpiperazines, Benzolactams, Dopamine receptors, Structure-activity relationshipAutores:Brea J., Filipe Miguel Areias, López L., Loza M.I., Masaguer C.F., Ortega R., Pastor M., Raviña E., Sanz F., Selent J.Fuentes:googlescopusSynthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics
ArticleAbstract: The complex etiology of schizophrenia has prompted researchers to develop clozapine-related multitarPalabras claves:Autores:Aranda R., Brea J., Domínguez E., Filipe Miguel Areias, López L., Loza M.I., Masaguer C.F., Pastor M., Raviña E., Sanz F., Selent J., Villalba K.Fuentes:googlescopus