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Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
ArticleAbstract: Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice due to theirPalabras claves:Alzheimer's disease, benzodiazepines, COGNITION, dementia, RISK FACTORSAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusCurrent Research Therapeutic Strategies for Alzheimer's Disease Treatment
ReviewAbstract: Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the developed coPalabras claves:Autores:Abad S., Antoni Camins, Auladell C., Ettcheto M., Folch J., García M.L., Olloquequi J., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusDexibuprofen ameliorates peripheral and central risk factors associated with Alzheimer’s disease in metabolically stressed APPswe/PS1dE9 mice
ArticleAbstract: Background: Several studies stablished a relationship between metabolic disturbances and Alzheimer´sPalabras claves:Alzheimer´s disease, APPswe/PS1dE9, Cognitive deficits, Dexibuprofen, High fat diet, Metabolic alterations, neuroinflammation, synapsis, unfolded protein response, βA plaquesAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Carrasco M., Espinosa-Jimenez T., Ettcheto M., Folch J., Herrera K., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusDexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
ArticleAbstract: The aim of the present study is to elucidate the neuronal pathways associated to NSAIDs causing a rePalabras claves:Alzheimer's disease, APPswe/PS1dE9, Dexibuprofen, hippocampus, insulin receptor, Memory impairment, Mitochondria, TauAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., García M.L., Olloquequi J., Pallás M., Pons L., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusExcitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications
ReviewAbstract: Neurological and psychiatric disorders are leading contributors to the global disease burden, havingPalabras claves:Alzheimer’s disease, Autism Spectrum Disorder, Depression, glutamate, strokeAutores:Antoni Camins, Auladell C., Binvignat O., Cornejo-Córdova E., Olloquequi J., Soriano F.X., Verdaguer E.Fuentes:scopusImpact of New Drugs for Therapeutic Intervention in Alzheimer’s Disease
ReviewAbstract: The increases in population ageing and growth are leading to a boosting in the number of people liviPalabras claves:clinical studies, dementia, neuroinflammation, novel therapies, synapsesAutores:Antoni Camins, Auladell C., Cano A., Carrasco M., Espinosa T., Ettcheto M., Folch J., Gudiño-Cabrera G., Olloquequi J., Sanchez-Lopez E., Ureña-Guerrero M.E., Verdaguer E., Zárate C.B.Fuentes:scopusInvolvement of JNK1 in Neuronal Polarization During Brain Development
ReviewAbstract: The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control oPalabras claves:asymmetric division, DCX, JNK1, MAP1B, MIGRATION, NMDAR, SCG10, synaptogenesis, WDR62Autores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Olloquequi J., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusJNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy
ArticleAbstract: Neurogenesis in the adult dentate gyrus (DG) of the hippocampus allows the continuous generation ofPalabras claves:adult hippocampal neurogenesis, JNK isoforms, Kainic acid, Knockout miceAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Landa J., Olloquequi J., Rabaza M., Verdaguer E., Zárate C.B.Fuentes:scopusReview of the advances in treatment for Alzheimer disease: Strategies for combating β-amyloid protein
OtherAbstract: Introduction Alzheimer disease (AD) is a major neurodegenerative disorder which eventually results iPalabras claves:Alzheimer disease, Amyloid hypotheses, Beta-amyloid, Beta-secretase, Gamma-secretaseAutores:Abad S., Antoni Camins, Ettcheto M., Folch J., Miguel Marin, Olloquequi J., Pedros I., Petrov D.Fuentes:scopusRole of JNK isoforms in the kainic acid experimental model of epilepsy and neurodegeneration
ReviewAbstract: Chemoconvulsants that induce status epilepticus in rodents have been widely used over the past decadPalabras claves:apoptosis, C-Jun N-terminal kinase signaling pathway, hippocampus, Kainic acid, neuroprotection, ReviewAutores:Antoni Camins, Auladell C., Busquets O., De Lemos M.L., Ettcheto M., Folch J., Lazarowski A., Olloquequi J., Verdaguer E., Zárate C.B.Fuentes:scopus