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scopus(16)
A metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusA novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet
ArticleAbstract: Background: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the globaPalabras claves:Alzheimer’s disease, BACE1, BDNF, cognitive decline, dendritic spines, high-fat diet, neuroinflammation, Rhein-huprine hybrid, Tau, TLR4Autores:Antoni Camins, Auladell C., Bulló M., Cano A., Espinosa-Jimenez T., Ettcheto M., Folch J., Muñoz-Torrero D., Olloquequi J., Parcerisas A., Pont C., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
ReviewAbstract: Alzheimer's disease (AD) represents a global burden in the economics of healthcare systems. Amyloid-Palabras claves:ADAM10, Alzheimer's disease, Natural compounds, Pharmaceutical, α-SecretaseAutores:Antoni Camins, Busquets O., Cano A., Cominetti M.R., Di Luca M., Endres K., Ettcheto M., Manzine P.R., Marcello E., Olloquequi J., Pelucchi S.Fuentes:scopusEarly Preclinical Changes in Hippocampal CREB-Binding Protein Expression in a Mouse Model of Familial Alzheimer’s Disease
ArticleAbstract: The molecular basis of memory loss in Alzheimer’s disease (AD), the main cause of senile dementia, iPalabras claves:Alzheimer disease, APPswe/PS1dE9, CBP, CREB, hippocampusAutores:Abad S., Antoni Camins, Auladell C., Busquets O., Carro E., Casadesús G., Ettcheto M., Folch J., Olloquequi J., Pallás M., Pedros I., Petrov D., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusDexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
ArticleAbstract: The aim of the present study is to elucidate the neuronal pathways associated to NSAIDs causing a rePalabras claves:Alzheimer's disease, APPswe/PS1dE9, Dexibuprofen, hippocampus, insulin receptor, Memory impairment, Mitochondria, TauAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., García M.L., Olloquequi J., Pallás M., Pons L., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusExperimental models for aging and their potential for novel drug discovery
ReviewAbstract: Background: An interesting area of scientific research is the development of potential antiaging druPalabras claves:aging, Heterogeneous mice model, IGF-1, mTOR, Resveratrol, SAMP8, SirtuinsAutores:Antoni Camins, Auladell C., Busquets O., Casadesús G., Ettcheto M., Folch J., Miguel Marin, Olloquequi J., Pallás M., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusImpact of New Drugs for Therapeutic Intervention in Alzheimer’s Disease
ReviewAbstract: The increases in population ageing and growth are leading to a boosting in the number of people liviPalabras claves:clinical studies, dementia, neuroinflammation, novel therapies, synapsesAutores:Antoni Camins, Auladell C., Cano A., Carrasco M., Espinosa T., Ettcheto M., Folch J., Gudiño-Cabrera G., Olloquequi J., Sanchez-Lopez E., Ureña-Guerrero M.E., Verdaguer E., Zárate C.B.Fuentes:scopusInvolvement of JNK1 in Neuronal Polarization During Brain Development
ReviewAbstract: The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control oPalabras claves:asymmetric division, DCX, JNK1, MAP1B, MIGRATION, NMDAR, SCG10, synaptogenesis, WDR62Autores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Olloquequi J., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusJNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy
ArticleAbstract: Neurogenesis in the adult dentate gyrus (DG) of the hippocampus allows the continuous generation ofPalabras claves:adult hippocampal neurogenesis, JNK isoforms, Kainic acid, Knockout miceAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Landa J., Olloquequi J., Rabaza M., Verdaguer E., Zárate C.B.Fuentes:scopusReview of the advances in treatment for Alzheimer disease: Strategies for combating β-amyloid protein
OtherAbstract: Introduction Alzheimer disease (AD) is a major neurodegenerative disorder which eventually results iPalabras claves:Alzheimer disease, Amyloid hypotheses, Beta-amyloid, Beta-secretase, Gamma-secretaseAutores:Abad S., Antoni Camins, Ettcheto M., Folch J., Miguel Marin, Olloquequi J., Pedros I., Petrov D.Fuentes:scopus