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A new multi-charged C<inf>60</inf> derivative: Synthesis and biological properties
ArticleAbstract: A new water-soluble multi-charged monoadduct fullero[60]pyrrolidine derivative with three ethylene gPalabras claves:Bioorganic chemistry, Cycloaddition, Fullerenes, neuroprotectionAutores:Antonelli T., Christian Larroque, Cusan C., Da Ros T., Ferraro L., Foley S., Janot J.M., Prato M., Seta P., Spalluto G., Tomasini M.C.Fuentes:scopusAcute Cocaine Enhances Dopamine D<inf>2</inf>R Recognition and Signaling and Counteracts D<inf>2</inf>R Internalization in Sigma1R-D<inf>2</inf>R Heteroreceptor Complexes
ArticleAbstract: The current study was performed to establish the actions of nanomolar concentrations of cocaine, notPalabras claves:Cocaine, dimerization, dopamine D2 receptor, Heteroreceptor complexes, Oligomerization, Sigma 1 receptor, Substance use disorderAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Narváez M., Pinton L., Tanganelli S., W. Romero-Fernandez, Wydra K.Fuentes:scopusAcute cocaine treatment enhances the antagonistic allosteric adenosine A2A-dopamine D2 receptor–receptor interactions in rat dorsal striatum without increasing significantly extracellular dopamine levels
ArticleAbstract: Background: Antagonistic adenosine A2A receptor (A2AR)-dopamine D2 receptor (D2R) receptor–receptorPalabras claves:Adenosine A2A receptor, Cocaine, dopamine D2 receptor, Heteroreceptor complexes, Sigma1 receptorAutores:Beggiato S., Borroto-Escuela D.O., Ferraro L., Filip M., Fuxe K., Tanganelli S., W. Romero-Fernandez, Wydra K., Zhou Z.Fuentes:scopusGPCR heteromers and their allosteric receptor-receptor interactions
ArticleAbstract: The concept of intramembrane receptor-receptor interactions and evidence for their existences were iPalabras claves:Adenosine receptor, allosteric modulation, Dopamine receptors, GPCR, moonlighting, Oligomers, Receptor G protein coupling, Receptor interface, Receptor mosaic, Receptor recognition, Receptor signaling, Receptor trafficking, Triplet homologiesAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Ferraro L., Filip M., Frankowska M., Fuxe K., Guidolin D., Marcellino D., Tanganelli S., Tarakanov A.O., W. Romero-Fernandez, Woods A.S.Fuentes:scopusExtrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks
ArticleAbstract: Extrasynaptic neurotransmission is an important short distance form of volume transmission (VT) andPalabras claves:Extrasynaptic, G protein coupled receptors, Heteromers, Neurotransmission, Receptor-receptor interactions, Striatal networks, Volume transmission, Wiring transissionAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Díaz-Cabiale Z., Ferraro L., Fuxe K., Garriga P., Guescini M., Narvaez J.A., Rivera A., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDiversity and bias through receptor-receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
ReviewAbstract: Allosteric receptor-receptor interactions in GPCR heteromers appeared to introduce an intermolecularPalabras claves:allosteric modulation, Biased recognition, Biased signaling, G protein-coupled receptor, Heterodimerization, Receptor diversity, Receptor heterodimers, Receptor-receptor interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Díaz-Cabiale Z., Ferraro L., Filip M., Fuxe K., Garriga P., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 heteroreceptor complexes and their receptor-receptor interactions in ventral striatum: Novel targets for antipsychotic drugs
Book PartAbstract: This review is focused on the D2 heteroreceptor complexes within the ventral striatum with their recPalabras claves:D2 receptors, Heteroreceptor complexes, Receptor-receptor interactions, Schizophrenia, Ventral striatumAutores:Agnati L.F., Borroto-Escuela D.O., Di Palma M., Ferraro L., Fuxe K., Pérez-Alea M., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers
ArticleAbstract: Biochemical, histochemical and coimmunoprecipitation experiments have indicated the existence of antPalabras claves:allosteric modulation, Dopamine D R receptor 2, G protein-coupled receptors, Heteromerization, Neurotensin 1 receptor, protein-protein interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Brito I., Corrales F., Ferraro L., Fuxe K., Narváez M., Ravani A., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusUnderstanding the balance and integration of volume and synaptic transmission. Relevance for psychiatry
ReviewAbstract: The major difference of synaptic transmission vs volume transmission (VT) is about the channels whicPalabras claves:G protein coupled receptors, neuroinflammation, Receptor-receptor interactions, Schizophrenia, Toxoplasma gondii, Volume transmissionAutores:Agnati L.F., Borroto-Escuela D.O., Cullheim S., Díaz-Cabiale Z., Ferraro L., Filip M., Fuxe K., Guidolin D., Manger P., Perez de la Mora M., Rivera A., Skieterska K., Tanganelli S., Tarakanov A.O., Van Craenenbroeck K., W. Romero-FernandezFuentes:scopusReceptor–receptor interactions in multiple 5-HT1A heteroreceptor complexes in raphe-hippocampal 5-HT transmission and their relevance for depression and its treatment
ReviewAbstract: Due to the binding to a number of proteins to the receptor protomers in receptor heteromers in the bPalabras claves:Depression, Fibroblast growth factor receptor, G protein-coupled receptors, Galanin, Heteroreceptor complexes, Oligomerization, Receptor tyrosine kinase, Receptor-receptor interactions, Serotonin 5-HT1A receptorAutores:Ambrogini P., Andrade-Talavera Y., Borroto-Escuela D.O., Brito I., Díaz-Cabiale Z., Ferraro L., Flores-Burgess A., Fuxe K., Gago B., Millón C., Narvaez J.A., Narváez M., Odagaki Y., Palkovits M., W. Romero-FernandezFuentes:scopus