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Pitfalls in characterizing P450c17 mutations associated with isolated 17,20-lyase deficiency
ArticleAbstract: The cytochrome P450c17 enzyme system performs both the 17α-hydroxylase and 17,20-lyase reactions inPalabras claves:Autores:Geller D.H., Gupta M.K., Richard J. AuchusFuentes:scopusThe genetic and functional basis of isolated 17, 20-lyase deficiency
OtherAbstract: Human male sexual differentiation requires production of fetal testicular testosterone, whose biosynPalabras claves:Autores:Geller D.H., Mendonça B.B., Miller W.L., Richard J. AuchusFuentes:scopusThe molecular basis of isolated 17,20 lyase deficiency
Conference ObjectAbstract: Human P450c17 catalyzes the 17α-hydroxylation of pregnenolone to 17OH pregnenolone and of progesteroPalabras claves:Autores:Geller D.H., Miller W.L., Richard J. AuchusFuentes:scopus