Mostrando 5 resultados de: 5
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Journal of Clinical Endocrinology and Metabolism(2)
Journal of Pediatric Endocrinology and Metabolism(1)
Nature Genetics(1)
Trends in Endocrinology and Metabolism(1)
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Fisiología humana(4)
Farmacología y terapéutica(3)
Ginecología, obstetricia, pediatría, geriatría(2)
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scopus(5)
Enzymatic activities of P450c17 stably expressed in fibroblasts from patients with the polycystic ovary syndrome
ArticleAbstract: Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting approximately 5-10% of womPalabras claves:Autores:Arlt W., Dunaif A., Geller D.H., Martens J.W.M., Miller W.L., Ossovskaya V.S., Richard J. Auchus, Rodriguez H.Fuentes:scopusPitfalls in characterizing P450c17 mutations associated with isolated 17,20-lyase deficiency
ArticleAbstract: The cytochrome P450c17 enzyme system performs both the 17α-hydroxylase and 17,20-lyase reactions inPalabras claves:Autores:Geller D.H., Gupta M.K., Richard J. AuchusFuentes:scopusThe function and roles of P450c17 in androgen excess states
Conference ObjectAbstract: Cytochrome P450c17 is a multifunctional enzyme that converts C21 steroids to the C19 sex steroid prePalabras claves:17,20-Lyase, 17-Hydroxylase, 3β-Hydroxysteroid dehydrogenase/Δ(5/4)-isomerase, adrenarche, Dehydroepiandrosterone, P450c17, Polycystic ovary syndrome, steroidogenesisAutores:Geller D.H., Lee T.C., Richard J. Auchus, Worthy K.Fuentes:scopusThe genetic and functional basis of isolated 17, 20-lyase deficiency
OtherAbstract: Human male sexual differentiation requires production of fetal testicular testosterone, whose biosynPalabras claves:Autores:Geller D.H., Mendonça B.B., Miller W.L., Richard J. AuchusFuentes:scopusThe regulation of human P450c17 activity: Relationship to premature adrenarche, insulin resistance and the polycystic ovary syndrome
ArticleAbstract: The polycystic ovary syndrome (PCOS) is characterized by hyperandrogenism and insulin resistance, buPalabras claves:Autores:Geller D.H., Lee T.C., Miller W.L., Richard J. AuchusFuentes:scopus