P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b<inf>5</inf>

Article

Abstract: Cytochrome P450c17 catalyzes steroid 17α-hydroxylase and 17,20-lyase activities and hence is a key e

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Autores:

Geller D.H., Miller W.L., Richard J. Auchus

Fuentes:

scopus