Mostrando 7 resultados de: 7
Filtros aplicados
Publisher
Toxicon(3)
BioMed Research International(1)
International Journal of Biological Macromolecules(1)
International Journal of Quantum Chemistry(1)
Protein Journal(1)
Área temáticas
Farmacología y terapéutica(7)
Bioquímica(4)
Fisiología humana(1)
Fisiología y materias afines(1)
Medicina y salud(1)
Origen
scopus(7)
Molecular modeling of the inhibition of enzyme PLA<inf>2</inf> from snake venom by dipyrone and 1-phenyl-3-methyl-5-pyrazolone
Conference ObjectAbstract: Phospholipases A2 (PLA2) are enzymes that trigger the degradation cascade of the arachidonic acid, lPalabras claves:DFT, Dipyrone, molecular modeling, OPLS, PLA 2Autores:Baldasso P.A., Bezerra E.R.M., Calgarotto A.K., Chaar J.S., Comar M., Marangoni S., Oliveira A.R.M., Oliveira K.M.T., Saulo L. Silva, Veber C.L., Villar J.A.F.P.Fuentes:scopusPharmacological study of edema and myonecrosis in mice induced by venom of the bushmaster snake (Lachesis muta muta) and its basic Asp49 phospholipase A<inf>2</inf> (LmTX-I)
ArticleAbstract: Previous in vitro studies show that Lachesis muta venom and its purified Asp49 phospholipase A2, namPalabras claves:EDEMA, inflammation, Lachesis m. muta, Myotoxicity, Phospholipase A 2Autores:Calgarotto A.K., Cintra M., Da Cruz Höfling M.A., Damico D.C.S., Leonardo M.B., Marangoni S., Saulo L. SilvaFuentes:scopusLmrTX, a basic PLA<inf>2</inf> (D49) purified from Lachesis muta rhombeata snake venom with enzymatic-related antithrombotic and anticoagulant activity
ArticleAbstract: A basic phospholipase A2 (LmrTX) isoform was isolated from Lachesis muta rhombeata snake venom and pPalabras claves:Anticoagulant activity, Arterial thrombosis, Lachesis muta rhombeata venom, Phospholipase A 2, Photochemical injury, Platelet aggregationAutores:Antunes E., Damico D.C.S., de Souza R.C.G., Marangoni S., Mendes C.B., Nery-Diez A.C.C., Saulo L. Silva, Torres-Huaco F.D., Vassequi-Silva T., Vicente C.P., Werneck C.C.Fuentes:scopusSnake venom PLA<inf>2</inf>s inhibitors isolated from brazilian plants: Synthetic and natural molecules
ReviewAbstract: Ophidian envenomation is an important health problem in Brazil and other South American countries. IPalabras claves:Autores:Carvalho B.M.A., de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Marchi-Salvador D.P., Marcussi S., Martins W., Resende L.M., Santos J.D.L., Saulo L. Silva, Soares A.M., Stábeli R.G., Xavier B.M.Fuentes:scopusStructural, enzymatic and pharmacological profiles of AplTX-II - A basic sPLA<inf>2</inf> (D49) isolated from the Agkistrodon piscivorus leucostoma snake venom
ArticleAbstract: A basic sPLA2 (D49) from the venom of snake Agkistrodon piscivorus leucostoma (AplTX-II) was isolatePalabras claves:Agkistrodon piscivorus leuscostoma, Basic sPLA D49 2, molecular modeling, NOBA (4-nitro-3-octanoyloxy benzoic acid)Autores:Fernandes P.A., José Rafael de Almeida, Marangoni S., Ramos M.J., Resende L.M., Saulo L. Silva, Soares A.M., Tatiana A. Guaraca-Medina, Viegas M.F.Fuentes:scopusSynthesis and evaluation of nitrostyrene derivative compounds, new snake venom phospholipase A<inf>2</inf> inhibitors
ArticleAbstract: Several nitrostyrene derivatives were synthesized and their inhibitive activities on phospholipase APalabras claves:Bothrops jararacussu, Chemometrics, DFT, Nitrostyrene, PLA 2Autores:Calgarotto A.K., Lima F.T.D., Marangoni S., Oliveira A.R.M., Saulo L. Silva, Veber C.L., Villar J.A.F.P.Fuentes:scopusSynthesis and evaluation of sesquiterpene lactone inhibitors of phospholipase A2 from Bothrops jararacussu
ArticleAbstract: Several sesquiterpene lactone were synthesized and their inhibitive activities on phospholipase A2 (Palabras claves:Bothrops jararacussu, Chemometrics, DFT, PLA2, Sesquiterpene lactoneAutores:Barosa L.C.A., de Alvarenga E.S., Demuner A.J., Ferreira J.M.S., Granjeiro P.A., Marangoni S., Marcussi S., Parreira A.G., Resende R.R., Ribeiro R.I.M.A., Saulo L. Silva, Silva J.A., Silva S.A., Soares A.M.Fuentes:scopus