Mostrando 10 resultados de: 20
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Toxicon(8)
European Journal of Medicinal Chemistry(2)
International Journal of Peptide Research and Therapeutics(2)
Journal of Molecular Structure: THEOCHEM(2)
BioMed Research International(1)
CoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., José Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googlescopusBiochemical and functional studies of ColTx-I, a new myotoxic phospholipase A<inf>2</inf> isolated from Crotalus oreganus lutosus (Great Basin rattlesnake) snake venom
ArticleAbstract: Commonly, phospholipases A2 (PLA2s) play key roles in the pathogenesis of the local tissue damage chPalabras claves:Biological activities, Crotalus oreganus lutosus, Myotoxin, Phospholipase A 2, Snake venomAutores:de Azevedo Calderon L., José Rafael de Almeida, Marangoni S., Resende L.M., Ribeiro R.I.M.A., Saulo L. Silva, Silva A.G., Soares A.M., Stábeli R.G.Fuentes:scopusBiological and biochemical characterization of new basic phospholipase A<inf>2</inf> BmTX-I isolated from Bothrops moojeni snake venom
ArticleAbstract: BmTX-I, an Asp49 phospholipase A2, was purified from Bothrops moojeni venom after only one chromatogPalabras claves:Asp49 phospholipase A2, characterization, Edema-forming activity, Myonecrosis and interleukin-6 response, Neuromuscular blockade, Snake venomAutores:Baldasso P.A., Calgarotto A.K., Damico D.C.S., Eberlin M.N., Marangoni S., Ponce-Soto L.A., Saulo L. Silva, Souza G.H.M.F.Fuentes:scopusA multivariate study on flavonoid compounds scavenging the peroxynitrite free radical
ArticleAbstract: The goal of this study is to select electronic properties (variables or descriptors) responsible forPalabras claves:flavonoids, Free radicals, HCA, Knn, pattern recognition, PCa, PeroxinitriteAutores:Calgarotto A.K., Comar M., Da Silva A.B.F., Honório K.M., Marangoni S., Miotto S., Oliveira K.M.T., Saulo L. Silva, Silva J.L.Fuentes:scopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusCorrigendum to “Exploring and understanding the functional role, and biochemical and structural characteristics of an acidic phospholipase A2, AplTx-I, purified from Agkistrodon piscivorus leucostoma snake venom” [Toxicon 127 (2017) 22–36] (S004101011730003X) (10.1016/j.toxicon.2017.01.002)
OtherAbstract: 2.5.2. Homology modeling and molecular dynamic studies The homology model of AplTx-I were built (usiPalabras claves:Autores:Collaço R.C.O., de Azevedo Calderon L., González W., José Rafael de Almeida, Marangoni S., Ramírez D., Ramos R.S., Resende L.M., Saulo L. Silva, Simioni L.R., Soares A.M.Fuentes:scopusEffect of a pool of peptides isolated from crotalus durissus terrificus (South American Rattlesnake) venom on glucose levels of mice fed on a high-fat diet
ArticleAbstract: This study investigated the effect of a pool of peptides, isolated from venom of Crotalus durissus tPalabras claves:Bioactive peptides, Crotalus durissus terrificus, glucose, hyperglycemia, Snake venomAutores:Alberício F., Marangoni S., Martins-Santos M.E.S., Oliveira E., Pinto F.C.H., Resende R.R., Saulo L. Silva, Soares A.M.Fuentes:scopusMolecular modeling and inhibition of phospholipase A<inf>2</inf> by polyhydroxy phenolic compounds
ArticleAbstract: Phospholipases A2 are enzymes responsible for the hydrolysis of membrane phospholipids that releasePalabras claves:DFT, Enzymatic kinetics, molecular modeling, PHENOLIC COMPOUNDS, PLA 2Autores:Baldasso P.A., Calgarotto A.K., Comar M., Damico D.C.S., Marangoni S., Maso V., Oliveira A.R.M., Oliveira K.M.T., Saulo L. Silva, Veber C.L., Villar J.A.F.P.Fuentes:scopusMolecular modeling of the inhibition of enzyme PLA<inf>2</inf> from snake venom by dipyrone and 1-phenyl-3-methyl-5-pyrazolone
Conference ObjectAbstract: Phospholipases A2 (PLA2) are enzymes that trigger the degradation cascade of the arachidonic acid, lPalabras claves:DFT, Dipyrone, molecular modeling, OPLS, PLA 2Autores:Baldasso P.A., Bezerra E.R.M., Calgarotto A.K., Chaar J.S., Comar M., Marangoni S., Oliveira A.R.M., Oliveira K.M.T., Saulo L. Silva, Veber C.L., Villar J.A.F.P.Fuentes:scopusPharmacological study of edema and myonecrosis in mice induced by venom of the bushmaster snake (Lachesis muta muta) and its basic Asp49 phospholipase A<inf>2</inf> (LmTX-I)
ArticleAbstract: Previous in vitro studies show that Lachesis muta venom and its purified Asp49 phospholipase A2, namPalabras claves:EDEMA, inflammation, Lachesis m. muta, Myotoxicity, Phospholipase A 2Autores:Calgarotto A.K., Cintra M., Da Cruz Höfling M.A., Damico D.C.S., Leonardo M.B., Marangoni S., Saulo L. SilvaFuentes:scopus