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Gene prioritization through consensus strategy, enrichment methodologies analysis, and networking for osteosarcoma pathogenesis
ArticleAbstract: Osteosarcoma is the most common subtype of primary bone cancer, affecting mostly adolescents. In recPalabras claves:Communality analysis, early recognition, Gene prioritization, Osteosarcoma, pathogenesisAutores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, Gabriela Fernanda Jaramillo-Koupermann, González‐díaz H., Munteanu C.R., Sierra A.P., Yunierkis Perez-CastilloFuentes:scopusGene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
ArticleAbstract: Consensus strategy was proved to be highly efficient in the recognition of gene-disease association.Palabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopusHP-Lattice QSAR for dynein proteins: Experimental proteomics (2D-electrophoresis, mass spectrometry) and theoretic study of a Leishmania infantum sequence
ArticleAbstract: The toxicity and inefficacy of actual organic drugs against Leishmaniosis justify research projectsPalabras claves:2D-electrophoresis, BLAST, complex networks, Dyneins, HP-Lattice model, Leishmania infantum, Mass spectrometry, Parasites proteomics, QSAR, Sequence alignment, Spectral momentsAutores:Bolas-Fernández F., Chou K.C., Dea-Ayuela M.A., González‐díaz H., Meneses-Marcel A., Ubeira F.M., Yunierkis Perez-CastilloFuentes:googlescopusMulti-output model with box-jenkins operators of quadratic indices for prediction of malaria and cancer inhibitors targeting ubiquitin-proteasome pathway (UPP) proteins
ArticleAbstract: The ubiquitin-proteasome pathway (UPP) is the primary degradation system of short-lived regulatory pPalabras claves:Atom-based quadratic indices, Cáncer, CHEMBL, MALARIA, Moving average, Multi-scale and multi-output model, multi-target, QSAR, UPP inhibitorAutores:Abad C., Gerardo M. Casañola-Martin, González‐díaz H., Merino-Sanjuán M., Pérez-Giménez F., Thu H.L.T., Yovani Marrero-PonceFuentes:scopusNucleic acid quadratic indices of the "macromolecular graph's nucleotides adjacency matrix". Modeling of footprints after the interaction of paromomycin with the HIV-1 Ψ-RNA packaging region
ArticleAbstract: This report describes a new set of macromolecular descriptors of relevance to nucleic acid QSAR/QSPRPalabras claves:Footprinting, Nucleic Acid Quadratic Index, paromomycin, QSPR/QSAR, RNA HIV-1, TOMOCOMD-CANAR approachAutores:Castro E.A., De Armas R.R., González‐díaz H., Nodarse D., Torrens F., Yovani Marrero-Ponce, Zaldivar V.R.Fuentes:googlescopusOncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine
ArticleAbstract: Breast cancer (BC) is the leading cause of cancer-related death among women and the most commonly diPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., Santiago Xavier Guerrero, Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopusQSPR and Flow Cytometry Analysis (QSPR-FCA): Review and New Findings on Parallel Study of Multiple Interactions of Chemical Compounds with Immune Cellular and Molecular Targets
ReviewAbstract: The immune system helps to halt the infections caused by pathogenic microbial and parasitic agents.Palabras claves:CD19 lymphocytes, CHEMBL, complex networks, Drug immunotoxicity, Flow cytometry, Markov chains, perturbation theory, Spectral momentsAutores:Alejandro Speck-Planche, González‐díaz H., Luan F., Natalia Dias Soeiro Cordeiro M., Ramirez F.R., Tenorio-Borroto E.Fuentes:scopus