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A Manganese-independent Aldolase Enables Staphylococcus aureus To Resist Host-imposed Metal Starvation
ArticleAbstract: The preferred carbon source of Staphylococcus aureus and many other pathogens is glucose, and its coPalabras claves:aldolase, calprotectin, manganese, Nutritional immunity, STAPHYLOCOCCUS AUREUSAutores:Bastille T.S., Kehl-Fie T.E., Paola K. Párraga Solórzano, Radin J.N.Fuentes:scopusAcquisition of the phosphate transporter NptA enhances Staphylococcus aureus pathogenesis by improving phosphate uptake in divergent environments
ArticleAbstract: During infection, pathogens must obtain all inorganic nutrients, such as phosphate, from the host. DPalabras claves:Gram positive, infection, NptA, Phosphate metabolism, PitA, PstSCAB, STAPHYLOCOCCUS AUREUS, TransporterAutores:Degnan P., Grim K.P., Kehl-Fiea T.E., Kelliher J.L., Paola K. Párraga Solórzano, Radin J.N.Fuentes:scopusDisruption of phosphate homeostasis sensitizes staphylococcus aureus to nutritional immunity
ArticleAbstract: To control infection, mammals actively withhold essential nutrients, including the transition metalPalabras claves:calprotectin, infection, manganese, Nutritional immunity, Phosphate homeostasis, PstSCAB, STAPHYLOCOCCUS AUREUSAutores:Brazel E.B., Joya E.S., Kehl-Fiea T.E., Kelliher J.L., McDevitt C.A., Neville S.L., Paola K. Párraga Solórzano, Radin J.N.Fuentes:scopusIntracellular accumulation of staphylopine can sensitize staphylococcus aureus to host-imposed zinc starvation by chelation-independent toxicity
ArticleAbstract: The host restricts the availability of zinc to prevent infection. To overcome this defense, StaphyloPalabras claves:calprotectin, Nutritional immunity, Pseudopaline, STAPHYLOCOCCUS AUREUS, Staphylopine, ZincophoreAutores:Frye K.A., Ganio K., Grim K.P., Kehl-Fiea T.E., McDevitt C.A., Morey J.R., Neville S.L., Paola K. Párraga Solórzano, Radin J.N.Fuentes:scopusRole of respiratory NADH oxidation in the regulation of Staphylococcus aureus virulence
ArticleAbstract: The success of Staphylococcus aureus as a pathogen is due to its capability of fine-tuning its celluPalabras claves:NADH dehydrogenase, NADH/NAD +, Respiratory chain, STAPHYLOCOCCUS AUREUS, two-component systemAutores:Chen G.Y., Gennis R.B., Kehl-Fiea T.E., Lencina A.M., Paola K. Párraga Solórzano, Radin J.N., Sauer J.D., Schurig-Briccio L.A.Fuentes:scopusThe metallophore staphylopine enables staphylococcus aureus to compete with the host for zinc and overcome nutritional immunity
ArticleAbstract: During infection, the host sequesters essential nutrients, such as zinc, to combat invading microbesPalabras claves:calprotectin, CntABCDF, Nutritional immunity, Siderophores, STAPHYLOCOCCUS AUREUS, Staphylopine, ZincAutores:Brazel E.B., Grim K.P., Kehl-Fiea T.E., Kelliher J.L., Kim P., McDevitt C.A., Paola K. Párraga Solórzano, Radin J.N., San Francisco B.Fuentes:scopus