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A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm
ArticleAbstract: Background: Intrabodies are defined as antibody molecules which are ectopically expressed inside thePalabras claves:Autores:Bec N., Christian Larroque, Courtête J., Martineau P., Philibert P., Saven J.G., Sibler A.P., Stoessel A., Wang W., Weiss E.Fuentes:scopusCyclophilin A as negative regulator of apoptosis by sequestering cytochrome c
ArticleAbstract: The release of cytochrome c from the mitochondrial intermembrane space is a decisive event in prograPalabras claves:apoptosis, BRAIN, Cyclophilin A, Cytochrome c, Phosphatidylethanolamine-binding protein, Procaspase-3, TumorAutores:Bec N., Bonfils C., Christian Larroque, Gongora C., Martineau P., Pugniere M., Rio M.D.Fuentes:scopusSelection for intrabody solubility in mammalian cells using GFP fusions
ArticleAbstract: Single-chain antibody fragments (scFv) expressed in the cytoplasm of mammalian cells, also called inPalabras claves:aggregation, Degradation, folding, GFP, intrabodyAutores:Bec N., Christian Larroque, Dariavach P., Denis V., Guglielmi L., Martineau P., Vezzio-Vié N.Fuentes:scopusSpecific In Vivo Labeling of Tyrosinated α-Tubulin and Measurement of Microtubule Dynamics Using a GFP Tagged, Cytoplasmically Expressed Recombinant Antibody
ArticleAbstract: GFP-tagged proteins are used extensively as biosensors for protein localization and function, but thPalabras claves:Autores:Cassimeris L., Christian Larroque, Denis V., Guglielmi L., Martineau P.Fuentes:scopusTargeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells
ArticleAbstract: Spleen tyrosine kinase (Syk) expression have been both positively and negatively associated with tumPalabras claves:Autores:Bec N., Cassagnard N., Christian Larroque, Combès E., Cornillot E., Dariavach P., Denis V., Gongora C., Jarlier M., Jeanson L., Martineau P., Rio M.D., Robert B.Fuentes:scopus