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In-cell intrabody selection from a diverse human library identifies C12orf4 protein as a new player in rodent mast cell degranulation
ArticleAbstract: The high specificity of antibodies for their antigen allows a fine discrimination of target conformaPalabras claves:Autores:Bec N., Christian Larroque, Dariavach P., Desvignes J.P., Guglielmi L., Hahn C.S., Jupp R., Martineau P., Mazuc E., Mollevi C., Parez V., Parrinello H.Fuentes:scopusMALDI imaging mass spectrometry and chemometric tools to discriminate highly similar colorectal cancer tissues
ArticleAbstract: Intratumour heterogeneity due to cancer cell clonal evolution and microenvironment composition and tPalabras claves:Chemometrics, Colorectal cancer, MALDI imaging, Multivariate analysis, Tumor heterogeneityAutores:Bec N., Christian Larroque, de Juan A., Fernández L., Gongora C., Marco S., Martineau P., Mas S., Torro A.Fuentes:scopusUse of physiological information based on grayscale images to improve mass spectrometry imaging data analysis from biological tissues
ArticleAbstract: The characterization of cancer tissues by matrix-assisted laser desorption ionization-mass spectromePalabras claves:Grayscale images, K-Means, Local rank constraints, MALDI-MSI, MCR-ALSAutores:Bec N., Christian Larroque, de Juan A., Erschov G., Fernández L., Gongora C., Marco S., Martineau P., Mas S., Torro A.Fuentes:scopusTargeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells
ArticleAbstract: Spleen tyrosine kinase (Syk) expression have been both positively and negatively associated with tumPalabras claves:Autores:Bec N., Cassagnard N., Christian Larroque, Combès E., Cornillot E., Dariavach P., Denis V., Gongora C., Jarlier M., Jeanson L., Martineau P., Rio M.D., Robert B.Fuentes:scopus