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A novel biparatopic hybrid antibody-ACE2 fusion that blocks SARS-CoV-2 infection: implications for therapy
ArticleAbstract: In the absence of a proven effective vaccine preventing infection by SARS-CoV-2, or a proven drug toPalabras claves:antibody-ACE2 fusion, Biparatopic, covid-19, neutralizing antibody, SARS-COV-2Autores:Chen C., Chen L., Fu W., Gao W., Huang X., James W.S., Javier Gilbert Jaramillo, Jiang W., Knight M.L., Lee S.M.Y., Liu X., Luo Y., Miao X., Pang T., Rijal P., Song X., Sun J., Tan T.K., Tang Y., Townsend A.R., Tsun A., Wan L., Wang C., Wu F., Xu Y., Yan Y., Yuan Z., Zou Y.Fuentes:scopusInclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity
ArticleAbstract: Cyclic GMP-AMP (cGAMP) is an immunostimulatory molecule produced by cGAS that activates STING. cGAMPPalabras claves:cGAMP, Influenza a virus, SARS-COV-2, type I interferon, viral vaccine vectorAutores:Beveridge R., Borrow P., Bridgeman A., Chauveau L., Drakesmith H., Frost J.N., Javier Gilbert Jaramillo, Knight M.L., Liu X., Partridge T., Pedroza-Pacheco I., Rehwinkel J., Rijal P., Russell R.A., Tan T.K., Townsend A.R.Fuentes:scopusImmunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine
ArticleAbstract: Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was introduced in thePalabras claves:antibody, B cell, BNT162b2, covid-19, dosing interval, Neutralization, SARS-COV-2, T cell, Vaccine, variants of concernAutores:Abuelgasim H., Adele S., Adland E., Adlou S., Akther H.D., Al-Taei S., Alhussni A., Ali M., Altmann T., Amini A., Angyal A., Arancibia-Cárcamo C.V., Austin J.A., Azim Ansari M., Barnes E., Bayley M., Bridges-Webb A., Brown A., Brown H., Brown R., Carroll M.W., Chalk J., Chand M., Chawla A., Chinnakannan S., Conlon C.P., Cross A., Cutteridge J., de Lara C., de Silva T.I., Deeks A.S., Dejnirattisai W., Denly L., Diffey B., Dimitriadis S., Dobson S.L., Dold C., Donnison T., Drake T.M., Dunachie S.J., Duncan C.J.A., Dupont M., Eyre D.W., Fairman A., Faustini S., Foulkes S., Frater J., Gardiner S., Gillson N., Goulder P., Hackstein C.P., Hall V., Hambleton S., Haniffa M., Hargreaves A., Haworth J., Hering L.M., Holmes J., Hopkins S., Horner E., Hornsby H., Jämsén A., Javier Gilbert Jaramillo, Jeffery K., Johnson S.A., Jones C., Kasanyinga M., Kelly S., Kilby J.A., Kirk R., Klenerman P., Knight M.L., Lawrie A., Lee L., Linder A., Longet S., Malone T., Matthews P.C., Meardon N., Mongkolsapaya J., Moore S.C., Nicols A.R., Payne R.P., Phillips E., Pollard A.J., Reyes L.S., Richter A., Rowland-Jones S.L., Saei A., Sandhar G., Screaton G.R., Shields A., Skelly D.T., Stafford L., Supasa P., Tipton T., Turtle L., Tyerman J.K., Whitham R., Wootton D.G.Fuentes:scopusSARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus
ArticleAbstract: Background: Laboratory diagnosis of SARS-CoV-2 infection (the cause of COVID-19) uses PCR to detectPalabras claves:Biomarker, Blood, covid-19, Laboratory safety, RNA, SARS-COV-2, Viraemia, Viral loadAutores:Andersson M.I., Arancibia-Cárcamo C.V., Auckland K., Baillie J.K., Barnes E., Beneke T., Bibi S., Brooks T.J.G., Carroll M.W., Crook D.W., Dingle K., Dold C., Downs L.O., Dunn L., Eyre D.W., Harvala H., Hoosdally S., Ijaz S., James T., James W.S., Javier Gilbert Jaramillo, Jeffery K., Justice A., Klenerman P., Knight J.C., Knight M.L., Liu X., Lumley S.F., Matthews P.C., McNaughton A.L., Mentzer A.J., Mongkolsapaya J., Oakley S., Oliveira M.S., Peto T., Ploeg R.J., Ratcliff J., Robbins M.J., Roberts D.J., Rudkin J., Russell R.A., Screaton G.R., Semple M.G., Simmonds P., Skelly D.T., Stoesser N., Turtle L., Wareing S., Zambon M.Fuentes:scopus