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Admixture/fine-mapping in Brazilians reveals a West African associated potential regulatory variant (rs114066381) with a strong female-specific effect on body mass and fat mass indexes
ArticleAbstract: Background/objectives: Admixed populations are a resource to study the global genetic architecture oPalabras claves:Autores:Alvim I.O., Araujo G.S., Araújo N.M., Borda V., Choudhury A., Duarte Y.A.O., Dutil J., Gilman R.H., Gouveia M.H., Guio H., Hansen M.E.B., Horta B.L., Hsing A.W., Kehdy F.S.G., Leal T.P., Lima-Costa M.F., Lobo F., Luizon M.R., Lyra R., Machado M., Magalhães W.C.S., Mauricio L. Barreto, Mbulaiteye S.M., Mensah J., Michelin L.A., Naslavsky M.S., Norris S.A., O´Connor T.D., Passos-Bueno M.R., Peixoto S.V., Pereira A.C., Ramsay M., Rodrigues M.R., Santolalla M.L., Sant’Anna H.P., Scliar M.O., Tarazona-Santos E.M., Tishkoff S.A., Yamamoto G.L., Yeager M., Yeboah E., Zatz M., Zolini C.Fuentes:scopusGenomic ancestry, Self-rated health and its association with mortality in an admixed population: 10 year follow-up of the Bambui-Epigen (Brazil) cohort study of ageing
ArticleAbstract: Background: Self-rated health (SRH) has strong pbkp_redictive value for mortality in different contePalabras claves:Autores:Castro-Costa E., Cesar C.C., Firmo J.O.A., Horta B.L., Leal T.P., Lima-Costa M.F., Macinko J., Magalhães W.C.S., Mauricio L. Barreto, Peixoto S.V., Pereira A.C., Proietti F.A., Rodrigues M.R., Tarazona-Santos E.M., Vaz De Melo Mambrini J.Fuentes:scopusGenomic regions 10q22.2, 17q21.31, and 2p23.1 can contribute to a lower lung function in African descent populations
ArticleAbstract: Accumulated evidence supports the contribution of genetic factors in modulating airway function, espPalabras claves:Admixture mapping strategy, African ancestry, Lung function declineAutores:Araújo N.M., Cruz A.A., Figueiredo C.A.V., Fonseca H.F., Horta B.L., Lima N.P., Mauricio L. Barreto, Rios R., Santolalla M.L., Sant’Anna H.P., Saraiva M., Silva T.M., Tarazona-Santos E.M.Fuentes:scopus