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Applicability of ENCHANTED trial results to current acute ischemic stroke patients eligible for intravenous thrombolysis in England and Wales: Comparison with the Sentinel Stroke National Audit Programme registry
ArticleAbstract: Background: Randomized controlled trials provide high-level evidence, but the necessity to include sPalabras claves:acute ischemic stroke, Alteplase, Clinical trial, health outcomes, thrombolysisAutores:Arima H., Bath P.M.W., Bray B.D., Broderick J.P., Chalmers J., Durham A.C., Kim J.S., Lavados P.M., Lee T.H., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Paley L., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Rudd A.G., S Anderson C., Sharma V.K., Sprigg N., Wang J.G., Wang X., Woodward M.Fuentes:scopusInteraction of Blood Pressure Lowering and Alteplase Dose in Acute Ischemic Stroke: Results of the Enhanced Control of Hypertension and Thrombolysis Stroke Study
ArticleAbstract: Objective: To determine the extent to which the effects of intensive blood pressure (BP) lowering arPalabras claves:acute ischemic stroke, Blood pressure lowering, Hypertension, Intracerebral Hemorrhage, thrombolysisAutores:Arima H., Chalmers J., Delcourt C., Kim J.S., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Martins S.O., Minhas J.S., Moullaali T.J., Octavio Marques Pontes-Neto, Olavarria V.V., Robinson T.G., S Anderson C., Sandset E.C., Sharma V.K., Song L., Sun L., Thang N.H., Wang J.G., Wang X., Yang J.Fuentes:scopusLipid-lowering pretreatment and outcome following intravenous thrombolysis for acute ischaemic stroke: a post hoc analysis of the enhanced control of hypertension and thrombolysis stroke study trial
ArticleAbstract: Background: Debate exists as to whether statin pretreatment confers an increased risk of 90-day mortPalabras claves:Acute stroke outcome, Intracranial haemorrhage, Lipid-lowering therapy, OR, RISK FACTORS, statins, strokeAutores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Martins S.O., Minhas J.S., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Ricci S., Robinson T.G., S Anderson C., Sato S., Sharma V.K., Thang N.H., Wang J.G., Wang X., Woodward M.Fuentes:scopusRationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2×2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment
ArticleAbstract: Rationale: Controversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogPalabras claves:Acute ischaemic stroke, Alteplase, Dose, Hypertension, Rt-PA, thrombolysisAutores:Arima H., Bath P.M.W., Broderick J.P., Chalmers J., Chen X., Demchuk A.M., Donnan G.A., Fuentes S., Huang Y., Kim J.S., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Silva-Sieger F.A., Stapf C., Wang J.G., Woodward M.Fuentes:scopus