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Effects of intensive blood pressure lowering on cerebral ischaemia in thrombolysed patients: insights from the ENCHANTED trial
ArticleAbstract: Background: Intensive blood pressure lowering may adversely affect evolving cerebral ischaemia. We aPalabras claves:Acute ischaemic stroke, Blood pressure, Brain imaging, Cerebral infarction, Clinical trial, thrombolysisAutores:Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Chen C., Chen X., Delcourt C., Demchuk A.M., Donnan G.A., Lavados P.M., Levi C., Li G., Li Q., Lindley R.I., Liu L., Mair G., Martins S.O., Octavio Marques Pontes-Neto, Olavarria V.V., Ong S., Ouyang M., Parsons M.W., Robinson T.G., S Anderson C., Song L., Venturelli P.M., Wang X., Wardlaw J.M., Zhang G., Zhang L.Fuentes:scopusRationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2×2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment
ArticleAbstract: Rationale: Controversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogPalabras claves:Acute ischaemic stroke, Alteplase, Dose, Hypertension, Rt-PA, thrombolysisAutores:Arima H., Bath P.M.W., Broderick J.P., Chalmers J., Chen X., Demchuk A.M., Donnan G.A., Fuentes S., Huang Y., Kim J.S., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Silva-Sieger F.A., Stapf C., Wang J.G., Woodward M.Fuentes:scopus