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Biochimica et Biophysica Acta - Molecular Basis of Disease(2)
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scopus(4)
High-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
ArticleAbstract: Global obesity is a pandemic status, estimated to affect over 2 billion people, that has resulted inPalabras claves:Alzheimer disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Antoni Camins, Artiach G., Barroso E., Carro E., Casadesús G., Ferrer I., Folch J., Pallás M., Pedros I., Petrov D., Sureda F.X., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusPeripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease
ArticleAbstract: There is growing evidence that obesity associated with type 2 diabetes mellitus (T2DM) and aging arePalabras claves:Alzheimer’s disease, APPswe/PS1dE9, DIABÉTES, high-fat diet, Memantine, obesityAutores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusRole of brain c-Jun N-terminal kinase 2 in the control of the insulin receptor and its relationship with cognitive performance in a high-fat diet pre-clinical model
ArticleAbstract: Insulin resistance has negative consequences on the physiological functioning of the nervous system.Palabras claves:ER stress, high-fat diet, JNK, metabolism, neuroinflammation, PTP1BAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Eritja À., Ettcheto M., Folch J., López B.M., Manzine P.R., Olloquequi J., Vázquez-Carrera M., Verdaguer E.Fuentes:scopusTau hyperphosphorylation and increased BACE1 and RAGE levels in the cortex of PPARβ/δ-null mice
ArticleAbstract: The role of peroxisome proliferator activator receptor (PPAR)β/δ in the pathogenesis of Alzheimer'sPalabras claves:BACE1, Cortex, ERK1/2, PPARβ/δ, RAGE, TauAutores:Alberch J., Anglada-Huguet M., Antoni Camins, Barroso E., Del Valle J., Gutiérrez P., Michalik L., Pallás M., Palomer X., Porquet D., Rodriguez-Rodriguez R., Salvadó L., Vázquez-Carrera M., Vieira Santos A.M., Wahli W.Fuentes:scopus