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Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease
ArticleAbstract: There is growing evidence that obesity associated with type 2 diabetes mellitus (T2DM) and aging arePalabras claves:Alzheimer’s disease, APPswe/PS1dE9, DIABÉTES, high-fat diet, Memantine, obesityAutores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusPeroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations
ArticleAbstract: Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), the most PPAR abundant isotype in the centPalabras claves:dendritic spines, high-fat diet, insulin signaling, Memory impairment, neuroinflammation, PPARβ/δ, synapsis, T2DMAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Espinosa-Jimenez T., Ettcheto M., Folch J., Olloquequi J., Parcerisas A., Sanchez-Lopez E., Vázquez-Carrera M., Verdaguer E., Wahli W.Fuentes:scopusRole of brain c-Jun N-terminal kinase 2 in the control of the insulin receptor and its relationship with cognitive performance in a high-fat diet pre-clinical model
ArticleAbstract: Insulin resistance has negative consequences on the physiological functioning of the nervous system.Palabras claves:ER stress, high-fat diet, JNK, metabolism, neuroinflammation, PTP1BAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Eritja À., Ettcheto M., Folch J., López B.M., Manzine P.R., Olloquequi J., Vázquez-Carrera M., Verdaguer E.Fuentes:scopus