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Fructose-1,6-bisphosphate protects astrocytes from hypoxic damage
ArticleAbstract: To determine the effects of glucose and fructose-1,6-bisphosphate (FDP) on hypoxic cell damage, primPalabras claves:Autores:Chan P.H., George A. Gregory, Yu A.Fuentes:scopusEffects of neuroprotective dose of fructose-1,6-bisphosphate on hypoxia-induced expression of c-fos and hsp70 mRNA in neonatal rat cerebrocortical slices
ArticleAbstract: In situ hybridization (ISH) measurements of c-fos and hsp70 expression were made in brain slice studPalabras claves:brain slice, c-fos, FBP (fructose-1,6-bisphosphate), hsp70, Hypoxia, neonateAutores:Chan P.H., Espanol M., George A. Gregory, Hasegawa K., Litt L., Sharp F.Fuentes:scopusNOS inhibitors decrease hypoxia-induced ATP reductions in respiring cerebrocortical slices
ArticleAbstract: Background: Excess neuronal nitric oxide (NO) production might cause adenosine triphosphate loss andPalabras claves:Anoxia, Bioenergetics, Brain metabolism, Nitric oxide, Nuclear magnetic resonanceAutores:Beal M., Chan P.H., Chang L., Espanol M., George A. Gregory, Hasegawa K., James T., Litt L.Fuentes:scopusHypoxia-induced dysfunctions and injury of astrocytes in primary cell cultures
ArticleAbstract: The effects of severe hypoxia were studied in a primary culture of astrocytes prepared from newbornPalabras claves:Autores:Chan P.H., George A. Gregory, Yu A.Fuentes:scopusResponse of cerebral endothelial cells to hypoxia: modification by fructose-1,6-bisphosphate but not glutamate receptor antagonists
ArticleAbstract: Damage to the cerebral endothelium from ischemia could exacerbate brain injury by altering vascularPalabras claves:endothelial cell, fructose-1,6-bisphosphate, glutamate, Hypoxia, ischemia, MK-801Autores:Chan P.H., Chan T.Y.Y., George A. Gregory, Gobbel G.Fuentes:scopusProtection of astrocytes by fructose 1,6-bisphosphate and citrate ameliorates neuronal injury under hypoxic conditions
ArticleAbstract: Fructose 1,6-bisphosphate (FBP) protects astrocytes from hypoxic injury in vitro. To determine whethPalabras claves:citric acid, Co-culture, Fluorocitrate, Fructose 1,6- bisphosphate, Mixed culture, pentose phosphate pathwayAutores:Chan P.H., Chan T.Y.Y., George A. Gregory, Kelleher J.A.Fuentes:scopus