Mostrando 7 resultados de: 7
Filtros aplicados
Subtipo de publicación
Article(7)
Publisher
Biochimica et Biophysica Acta - Biomembranes(3)
Archives of Biochemistry and Biophysics(1)
Journal of Physical Chemistry B(1)
Journal of Structural Biology(1)
Langmuir(1)
Anticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures
ArticleAbstract: Edelfosine is an anticancer drug with an asymmetric structure because, being a derivative of glyceroPalabras claves:Autores:Alessio Ausili, Corbalán-García S., De Godos A., Gómez-Murcia V., Gómez‐Fernández J.C., Martínez-Valera P., Teruel J.A., Torrecillas A.Fuentes:googlescopusEdelfosine is incorporated into rafts and alters their organization
ArticleAbstract: The effect of edelfosine (1-O-octadecyl-2-O-methyl-rac-glycero-3- phosphocholine or ET-18-OCH3) on mPalabras claves:Autores:Alessio Ausili, Aranda F.J., Corbalán-García S., De Godos A., Gajate C., Gómez‐Fernández J.C., Mollinedo F., Torrecillas A.Fuentes:googlescopusInteraction of the C-terminal domain of Bcl-2 family proteins with model membranes
ArticleAbstract: Bcl-2 family proteins are involved in the cell homeostasis by regulating programmed cell death. SomePalabras claves:apoptosis, Bak, BAX, BCL-2, Fluorescence, Protein-lipid interactionAutores:Alessio Ausili, Corbalán-García S., Gómez‐Fernández J.C., Martínez-Senac M., Torrecillas A.Fuentes:googlescopusMembrane docking mode of the C2 domain of PKCε: An infrared spectroscopy and FRET study
ArticleAbstract: The C2 domain of PKCε binds to negatively charged phospholipids but little is known so far about thePalabras claves:ATR-IR, C2 domains, Membrane docking, PKCεAutores:Alessio Ausili, Berglin M., Corbalán-García S., Egea-Jiménez A., Elwing H., Gómez‐Fernández J.C.Fuentes:googlescopusThe binding of different model membranes with PKCε C2 domain is not dependent on membrane curvature but affects the sequence of events during unfolding
ArticleAbstract: The C2 domain of novel protein kinases C (nPKC) binds to membranes in a Ca2+-independent way contribPalabras claves:Infrared spectroscopy, Membrane curvature, Model membranes, Protein kinase Cε, Protein unfoldingAutores:Alessio Ausili, Corbalán-García S., Gómez‐Fernández J.C.Fuentes:googlescopusThe interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids
ArticleAbstract: The C-terminal domain of the pro-apoptotic protein Bax (Bax-C) is supposed to act as a membrane anchPalabras claves:13 C-NMR, 31 P-NMR, apoptosis, BAX, MAS-NMR, Protein-lipid interactionAutores:Alessio Ausili, Corbalán-García S., De Godos A., Gómez‐Fernández J.C., Torrecillas A.Fuentes:googlescopusThe interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes
ArticleAbstract: Fourier transform infrared spectroscopy (FTIR) was used to study the secondary structure of peptidesPalabras claves:apoptosis, ATR-FTIR, BAX, Infrared spectroscopyAutores:Alessio Ausili, Corbalán-García S., Gómez‐Fernández J.C., Martínez-Senac M., Torrecillas A.Fuentes:googlescopus