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Archives of Biochemistry and Biophysics(3)
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Clotrimazole fluidizes phospholipid membranes and localizes at the hydrophobic part near the polar part of the membrane
ArticleAbstract: Clotrimazole (1‐[(2‐chlorophenyl)‐diphenylmethyl]‐imidazole) is an azole antifungal drug belonging tPalabras claves:Clotrimazole, Location, Membrane fluidity, Model membraneAutores:Alessio Ausili, Gómez‐Fernández J.C., Teruel J.A., Yakymenko I.Fuentes:googlescopusCorrelation between fluorescence and structure in the orange-emitting GFP-like protein, monomeric Kusabira Orange
ArticleAbstract: The mKO is the monomeric version of Kusabira Orange, a GFP-like protein emitting bright orange fluorPalabras claves:Fluorescent proteins, FTIR, mKO, Protein structure, Thermo-stabilityAutores:Alessio Ausili, D'Auria G., D’auria S., Gómez‐Fernández J.C., Marabotti A., Ortiz A., Staiano M., Torrecillas A.Fuentes:googlescopusCapsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface
ArticleAbstract: Capsaicin is the chemical responsible for making some peppers spicy hot, but additionally it is usedPalabras claves:1 H NOESY MAS NMR, 2 H NMR, Capsaicin, dsc, membranes, SAXD, WAXDAutores:A Ausili, Alessio Ausili, Corbalán-García S., De Godos A., Fernández-Martínez A., Gómez‐Fernández J.C., Schneider M., Torrecillas A.Fuentes:googlerraaescopusAlcohol dehydrogenase from the hyperthermophilic archaeon Pyrobaculum aerophilum: Stability at high temperature
ArticleAbstract: The structural and stability properties of a novel zinc-dependent alcohol dehydrogenase from the hypPalabras claves:Adh, dsc, FTIR, stability, Thermostable proteinsAutores:Alessio Ausili, Barbarisi A., D’auria S., Gómez‐Fernández J.C., Labella T., Rosso F., Vitale A.Fuentes:googlescopusEdelfosine is incorporated into rafts and alters their organization
ArticleAbstract: The effect of edelfosine (1-O-octadecyl-2-O-methyl-rac-glycero-3- phosphocholine or ET-18-OCH3) on mPalabras claves:Autores:Alessio Ausili, Aranda F.J., Corbalán-García S., De Godos A., Gajate C., Gómez‐Fernández J.C., Mollinedo F., Torrecillas A.Fuentes:googlescopusThe binding of different model membranes with PKCε C2 domain is not dependent on membrane curvature but affects the sequence of events during unfolding
ArticleAbstract: The C2 domain of novel protein kinases C (nPKC) binds to membranes in a Ca2+-independent way contribPalabras claves:Infrared spectroscopy, Membrane curvature, Model membranes, Protein kinase Cε, Protein unfoldingAutores:Alessio Ausili, Corbalán-García S., Gómez‐Fernández J.C.Fuentes:googlescopusThe increase in positively charged residues in cecropin D-like Galleria mellonella favors its interaction with membrane models that imitate bacterial membranes
ArticleAbstract: A comparative study of three synthetic peptides, namely neutral Cecropin D-like G. mellonella (WT) aPalabras claves:Antimicrobial peptide, calorimetry, Cationic charge, Galleria mellonella, Infrared spectroscopy, Peptide-membrane interactionsAutores:Alessio Ausili, Aranda F.J., Gómez‐Fernández J.C., Manrique-Moreno M., Oñate-Garzón J., Patiño E., Torrecillas A.Fuentes:googlescopusThe membrane binding kinetics of full-length PKCα is determined by membrane lipid composition
ArticleAbstract: Protein kinase Cα (PKCα) is activated by its translocation to the membrane. Activity assays show thePalabras claves:PIP 2, PKCα, Rapid kinetics, stopped-flowAutores:Alessio Ausili, Corbalán-García S., Egea-Jiménez A., Gómez‐Fernández J.C., Pérez-Lara A.Fuentes:googlescopusQuartz crystal microbalance with dissipation monitoring and the real-time study of biological systems and macromolecules at interfaces
ArticleAbstract: QCM-D technique is based on the physical phenomenon that generates an acoustic shear wave with an osPalabras claves:Cell at interfaces, Proteins at interfaces, QCM-DAutores:Alessio Ausili, Berglin M., Corbalán-García S., Elwing H., Gómez‐Fernández J.C.Fuentes:googlescopusRedox state of coenzyme Q<inf>10</inf> determines its membrane localization
ArticleAbstract: The interaction between oxidized (ubiquinone-10) and reduced (ubiquinol-10) coenzyme Qio with dimyriPalabras claves:Autores:Alessio Ausili, Aranda F.J., Corbalán-García S., De Godos A., Gómez‐Fernández J.C., Sánchez-Bautista S., Torrecillas A.Fuentes:googlescopus