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Biochimica Et Biophysica Acta Biomembranes(4)
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Edelfosine is incorporated into rafts and alters their organization
ArticleAbstract: The effect of edelfosine (1-O-octadecyl-2-O-methyl-rac-glycero-3- phosphocholine or ET-18-OCH3) on mPalabras claves:Autores:Alessio Ausili, Aranda F.J., Corbalán-García S., De Godos A., Gajate C., Gómez‐Fernández J.C., Mollinedo F., Torrecillas A.Fuentes:googlescopusA comparison of the location in membranes of curcumin and curcumin-derived bivalent compounds with potential neuroprotective capacity for Alzheimer's disease
ArticleAbstract: Curcumin and two bivalent compounds, namely 17MD and 21MO, both obtained by conjugation of curcuminPalabras claves:1 H NOESY MAS-NMR, 1H NOESY MAS-NMR, curcumin, dsc, Fluorescence quenching, membranesAutores:Alessio Ausili, Beltrán A., Candel A.M., Gómez-Murcia V., Gómez‐Fernández J.C., He L., Jiang Y., Teruel J.A., Torrecillas A., Zhang S.Fuentes:googlescopusThe interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids
ArticleAbstract: The C-terminal domain of the pro-apoptotic protein Bax (Bax-C) is supposed to act as a membrane anchPalabras claves:13 C NMR, 13C-NMR, 31 P-NMR, 31P-NMR, apoptosis, BAX, MAS-NMR, Protein-lipid interactionAutores:Alessio Ausili, Corbalán-García S., De Godos A., Gómez‐Fernández J.C., Torrecillas A.Fuentes:googlescopusThe interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes
ArticleAbstract: Fourier transform infrared spectroscopy (FTIR) was used to study the secondary structure of peptidesPalabras claves:apoptosis, ATR-FTIR, BAX, Infrared spectroscopyAutores:Alessio Ausili, Corbalán-García S., Gómez‐Fernández J.C., Martínez-Senac M., Torrecillas A.Fuentes:googlescopusThe membrane binding kinetics of full-length PKCα is determined by membrane lipid composition
ArticleAbstract: Protein kinase Cα (PKCα) is activated by its translocation to the membrane. Activity assays show thePalabras claves:PIP 2, PKCα, Rapid kinetics, stopped-flowAutores:Alessio Ausili, Corbalán-García S., Egea-Jiménez A., Gómez‐Fernández J.C., Pérez-Lara A.Fuentes:googlescopusThe vertical location of α-tocopherol in phosphatidylcholine membranes is not altered as a function of the degree of unsaturation of the fatty acyl chains
ArticleAbstract: α-Tocopherol is a natural preservative that prevents free radical chain oxidations in biomembranes.Palabras claves:Autores:Alessio Ausili, Aranda F.J., Corbalán-García S., De Godos A., Gómez‐Fernández J.C., Torrecillas A.Fuentes:googlescopusThe binding of different model membranes with PKCε C2 domain is not dependent on membrane curvature but affects the sequence of events during unfolding
ArticleAbstract: The C2 domain of novel protein kinases C (nPKC) binds to membranes in a Ca<sup>2+</sup>-independentPalabras claves:Infrared spectroscopy, Membrane curvature, Model membranes, Protein kinase Cε, Protein unfoldingAutores:Alessio Ausili, Corbalán-García S., Gómez‐Fernández J.C.Fuentes:googlescopusThe increase in positively charged residues in cecropin D-like Galleria mellonella favors its interaction with membrane models that imitate bacterial membranes
ArticleAbstract: A comparative study of three synthetic peptides, namely neutral Cecropin D-like G. mellonella (WT) aPalabras claves:Antimicrobial peptide, calorimetry, Cationic charge, Galleria mellonella, Infrared spectroscopy, Peptide-membrane interactionsAutores:Alessio Ausili, Aranda F.J., Edwin Patiño, Gómez‐Fernández J.C., Manrique-Moreno M., Oñate-Garzón J., Patiño E., Torrecillas A.Fuentes:googlescopusCorrelation between fluorescence and structure in the orange-emitting GFP-like protein, monomeric Kusabira Orange
ArticleAbstract: The mKO is the monomeric version of Kusabira Orange, a GFP-like protein emitting bright orange fluorPalabras claves:Fluorescent proteins, FTIR, mKO, Protein structure, Thermo-stabilityAutores:Alessio Ausili, D'Auria G., D’auria S., G. D'Auria, Gómez‐Fernández J.C., Marabotti A., Ortiz A., Staiano M., Torrecillas A.Fuentes:googlescopusCurcumin disorders 1,2-dipalmitoyl-sn-glycero-3-phosphocholine membranes and favors the formation of nonlamellar structures by 1,2-dielaidoyl-sn-glycero- 3-phosphoethanolamine
ArticleAbstract: Curcumin is a polyphenol present in turmeric, a spice widely used in Asian traditional medicine andPalabras claves:Autores:Alessio Ausili, Aranda F.J., Corbalán-García S., Godos A.D., Gómez‐Fernández J.C., Pérez-Lara A., Torrecillas A.Fuentes:googlescopus