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DNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons
ArticleAbstract: Cytoskeletal alteration is a key factor in neurodegenerative processes like Alzheimer's or ParkinsonPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, colchicine, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusEvaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells
ArticleAbstract: Caspase-3 is a key protein involved in the classical apoptosis mechanism in neurons, as in many othePalabras claves:Acute toxicity, apoptosis, Caspase-3, Cell-cycle, Cerebellar granule neurons, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Tajes M.Fuentes:scopusNeuronal in vitro models for the estimation of acute systemic toxicity
ArticleAbstract: The objective of the EU funded integrated project "ACuteTox" is to develop a strategy in which generPalabras claves:Acute systemic toxicity, ACuteTox, in vitro, Neurotoxicity endpointsAutores:Antoni Camins, Bal-Price A.K., Coecke S., Fabre N., Forsby A., Gustafsson H., Honegger P., Kinsner-Ovaskainen A., Pallás M., Rimbau V., Rodríguez-Farré E., Suñol C., Vericat J.A., Zurich M.G.Fuentes:scopus