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Asymmetric pictet-spengler reactions: Synthesis of 1,2,3,4-tetrahydroisoquinoline carboxylic acid (Tic) chimeras
ArticleAbstract: A preparatively simple diastereoselective synthesis of the amino acid chimera (1S,3S)-1,2,3,4-tetrahPalabras claves:amino acids, Cyclizations, Diastereoselectivity, heterocycles, QuinolinesAutores:Broxterman Q.B., Burger K., Duchateau A.L.L., Jan Spengler, Quaedflieg P.J.L.M., Schedel H., Sieler J.Fuentes:googlescopusAn efficient synthesis of N-phosphinoylmethylamino acids and some of their derivatives
ArticleAbstract: N-Phosphinoylmethylamino acid derivatives 11-18 are obtained in high yield on N-bromomethylation ofPalabras claves:Autores:Burger K., Jan SpenglerFuentes:googlescopusA new approach to N-methylaspartic, N-methylglutamic, and N-methyl-α- aminoadipic acid derivatives
ArticleAbstract: N-Methylaspartic acid derivatives and its homologues are obtained by a stereoconservative one-pot prPalabras claves:Hexafluoroacetone, N-Methyl- α-aminoadipic acid, N-Methylaspartic acid, N-Methylglutamic acid, N-Methylthiazol-4-yl-α-amino acidsAutores:Burger K., Jan SpenglerFuentes:scopusA new strategy for solid-phase depsipeptide synthesis using recoverable building blocks
ArticleAbstract: (Chemical Equation Presented) The technique of choice for synthesis of small-scale depsipeptides isPalabras claves:Autores:Alberício F., Burger K., Jan Spengler, Ruíz-Rodríguez J.Fuentes:googlescopusApplication of hexafluoroacetone as protecting and activating reagent in solid phase peptide and depsipeptide synthesis
ArticleAbstract: Hexafluoroacetone-protected/activated hydroxy acids [2,2- bis(trifluoromethyl)-1,3-dioxolan-4-ones]Palabras claves:Bidentate reagents, Citramalic acid, Hexafluoroacetone, Tetrahydroisoquinoline carboxylic acidAutores:Alberício F., Burger K., Cupido T., Jan Spengler, Ruiz J.Fuentes:googlescopusAbbreviated nomenclature for cyclic and branched homo- and hetero-detic peptides
ArticleAbstract: Amino acid sequences and linear or head-to-tail cyclopeptides can be represented conveniently in onePalabras claves:Abbreviated nomenclature, Branched peptides, Connected peptide strands, Cyclopeptides, One-line text formulae, RecommendationAutores:Alberício F., Burger K., Giralt E., Jan Spengler, Jiménez J.Fuentes:scopusDomino reactions with fluorinated five-membered heterocycles - Syntheses of trifluoromethyl substituted butenolides and γ-ketoacids
ArticleAbstract: A new approach to trifluoromethyl substituted butenolides and their thioanalogues is described startPalabras claves:2-Fluoro-3-trifluoromethylfurans, 2-Fluoro-3-trifluoromethylthiophenes, Domino reactions, Trifluoromethyl substituted butenolides, α-Trifluoromethyl-γ-keto acidsAutores:Alberício F., Burger K., Fuchs A., Greif D., Hennig L., Jan SpenglerFuentes:googlescopusDomino reactions with fluorinated five-membered heterocycles. α-Trifluoromethyl α-amino acids with unsaturated side-chains
ArticleAbstract: α-Trifluoromethyl α-amino acids with unsaturated side-chains have been prepared from 5-fluoro-4-trifPalabras claves:5-Fluoro-4-trifluoromethyloxazoles, Allyl alcohols, Claisen rearrangement, Farnesol, Geraniol, nucleophilic aromatic substitution, Propargyl alcohols, secondary structure, α-Trifluoromethyl α-amino acidsAutores:Alberício F., Burger K., Hennig L., Jan Spengler, Koksch B., Tsouker P.Fuentes:googlescopusNew routes to natural and non-natural amino acids
Conference ObjectAbstract:Palabras claves:Autores:Burger K., Jan Spengler, Pires R., Schedel H.Fuentes:googlescopusHexafluoroacetone as a protecting and activating reagent. N- and O-glycosylation of isoserine and isocysteine *
ArticleAbstract: Starting from HFA-protected malic and thiomalic acid a series of O- and N-glycoconjugates suitable fPalabras claves:Glycoconjugates, Glycosylamines, Hexafluoroacetone, Isocyanates, malic acid, Thiomalic acidAutores:Alberício F., Böttcher C., Burger K., Hennig L., Jan SpenglerFuentes:googlescopus