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CoaTx-II, a new dimeric Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom with bactericidal potential: Insights into its structure and biological roles
ArticleAbstract: Snake venoms are rich and intriguing sources of biologically-active molecules that act on target celPalabras claves:Antibacterial effect, Crotalus oreganus abyssus, Lys49 phospholipase A 2, Myotoxicity, Snake venomAutores:de Azevedo Calderon L., González W., José Rafael de Almeida, Lancellotti M., Marangoni S., Ramírez D., Saulo L. Silva, Soares A.M.Fuentes:googlescopusA novel synthetic peptide inspired on Lys49 phospholipase A<inf>2</inf> from Crotalus oreganus abyssus snake venom active against multidrug-resistant clinical isolates
ArticleAbstract: Currently, the evolving and complex mechanisms of bacterial resistance to conventional antibiotics aPalabras claves:Antibacterial activity, Biomimetic peptide, Phospholipase A 2, Snake venomAutores:Bruno Mendes, Fernandes P.A., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Marangoni S., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopusLessons from a Single Amino Acid Substitution: Anticancer and Antibacterial Properties of Two Phospholipase A<inf>2</inf>-Derived Peptides
ArticleAbstract: The membrane-active nature of phospholipase A2-derived peptides makes them potential candidates forPalabras claves:Agkistrodon, leucine, Membrane, Phenylalanine, Venom peptidesAutores:Alves C., Bruno Mendes, Fernandes P.A., Franchi G.C., Gomes P.A.D.C., José Rafael de Almeida, Lancellotti M., Passos Ó., Ramos M.J., Saulo L. Silva, Vale N.Fuentes:scopus