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G-protein-coupled receptors oligomerization: Emerging signaling units and new opportunities for drug design
ArticleAbstract: G-protein-coupled receptors (GPCRs) are a widespread family of transmembrane receptors with differenPalabras claves:Dimers, disease, drug design, G-protein-coupled receptors, ligand, OligomerizationAutores:Borroto-Escuela D.O., Fuxe K., Garriga P., Ramon E., Rivera D., Tena-Campos M., W. Romero-FernandezFuentes:scopusDiversity and bias through receptor-receptor interactions in GPCR heteroreceptor complexes. Focus on examples from dopamine D2 receptor heteromerization
ReviewAbstract: Allosteric receptor-receptor interactions in GPCR heteromers appeared to introduce an intermolecularPalabras claves:allosteric modulation, Biased recognition, Biased signaling, G protein-coupled receptor, Heterodimerization, Receptor diversity, Receptor heterodimers, Receptor-receptor interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Díaz-Cabiale Z., Ferraro L., Filip M., Fuxe K., Garriga P., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopus