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A genome-wide association study of asthma symptoms in Latin American children
ArticleAbstract: Background: Asthma is a chronic disease of the airways and, despite the advances in the knowledge ofPalabras claves:Asthma symptoms, CHILDREN, Genome-wide association, Latin AmericaAutores:Burchard E.G., Conceição J.S., Costa G.N.O., Del Rio Navarro B., Dudbridge F., Fiaccone R.L., Figueiredo C.A.V., Gouveia M.H., Hancock D.B., Horimoto A.V.R., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., London S., Magalhães W.C.S., Mauricio L. Barreto, Pereira A.C., Pino-Yanes M., Rodrigues L.C., Rodrigues M.R., Romieu I., Silva T.M., Strina A., Tarazona-Santos E.M.Fuentes:scopusA genome-wide association study of severe asthma exacerbations in Latino children and adolescents
ArticleAbstract: Severe asthma exacerbations are a major cause of school absences and healthcare costs in children, pPalabras claves:Autores:Acosta-Pérez E., Avila L., Bomberger J., Boutaoui N., Burchard E.G., Canino G., Celedón J.C., Chen W., Cloutier M.M., Eng C., Figueiredo C.A.V., Forno E., Han Y.Y., Herrera-Luis E., Hu D., Huntsman S., Kiedrowski M.R., Kim S., Koppelman G.H., Lasky-Su J., Mauricio L. Barreto, Oh S., Pino-Yanes M., Qi C., Rios R., Soto-Quiros M.E., Weiss S.T., Xu C.J., Yan Q., Zhang R.Fuentes:scopusAdenylyl cyclase type 9 gene polymorphisms are associated with asthma and allergy in Brazilian children
ArticleAbstract: Asthma is a chronic inflammatory disease of the respiratory tract. This heterogeneous disease is cauPalabras claves:ADCY9, allergy, Asthma, camp, polymorphism, T regulatory cellsAutores:Costa R.S., Figueiredo C.A.V., Mauricio L. Barreto, Neves N.M.A., Teixeira H.Fuentes:scopusGenetic polymorphism (rs6587666) in FLG protects from eczema in admixed Brazilian children population with high African ancestry
ArticleAbstract: Genetic variants in filaggrin (FLG) are key in eczema and are less common in Africans than in EuropePalabras claves:Allele, Atopic dermatitis, Filaggrin, FLG, SkinAutores:Celedón J.C., Costa R.D.S., Figueiredo C.A.V., Forno E., Magalhães da Silva T., Mauricio L. Barreto, Rios R., Strina A.Fuentes:scopusGenetic polymorphisms in vitamin D pathway influence 25(OH)D levels and are associated with atopy and asthma
ArticleAbstract: Background: Vitamin D deficiency or insufficiency, has been associated with atopy and lack of asthmaPalabras claves:25(OH)D, Asthma, Atopy, CYP24A1, CYP2R1, IgE, SNVs, VDR, vitamin DAutores:Andrade Belitardo E.M.M.D., Costa G.N.O., Costa R.D.S., Cruz A.A., de Araújo Sena F., de Santana M.B.R., Figueiredo C.A.V., Galvão A.A., Mauricio L. Barreto, Neves N.M.A.Fuentes:scopusGenetic variants in 17q12-21 locus and childhood asthma in Brazil: Interaction with Varicella zoster virus seropositivity
ArticleAbstract: Background: Asthma is a complex disease with worldwide public health relevance, is related to enviroPalabras claves:17q12-21, Atopy, childhood asthma, Varicella zosterAutores:Conceição J.S., Fiaccone R.L., Figueiredo C.A.V., Genser B., Mauricio L. Barreto, Neves N.M.A., Nunes de Oliveira Costa G., Rodrigues L.C., Silva T.M., Strina A.Fuentes:scopusGenetic variants in RORA are associated with asthma and allergy markers in an admixed population
ArticleAbstract: Asthma and allergy affect hundreds of millions of people from childhood to old age. In most of them,Palabras claves:Asthma, Atopic sensitization, polymorphism, RORAAutores:Carneiro V.L., Costa G.N.O., Costa R.D.S., Figueiredo C.A.V., Lima L.C., Marques C.R., Mauricio L. Barreto, Neves N.M.A., Queiroz G.d.A.Fuentes:scopusGenome-wide association study of asthma, total IgE, and lung function in a cohort of Peruvian children
ArticleAbstract: Background: Genetic ancestry plays a role in asthma health disparities. Objective: Our aim was to evPalabras claves:admixture, allergy, Ancestry, Asthma, genome wide association analyses, immunoglobulin E, lung function, PerúAutores:Akenroye A.T., Ampleford E.A., Barnes K.C., Bleecker E.R., Brunetti T., Campbell M., Chavan S., Checkley W., Cruz A.A., Daya M., Figueiredo C.A.V., Fonseca H.F., Hansel N.N., Hawkins G.A., Kanchan K., Mathias R.A., Mauricio L. Barreto, Meyers D.A., Ortega V.E., Pitangueira Teixeira H.M., Preethi Boorgula M., Rafaels N., Romero K., Shankar G., Winters A.Fuentes:scopusGenome-wide burden and association analyses implicate copy number variations in asthma risk among children and young adults from Latin America
ArticleAbstract: The genetic architecture of asthma was relatively well explored. However, some work remains in the fPalabras claves:Autores:Barbosa G.C.G., Costa G.N.O., Damasceno A.K.A., Fiaccone R.L., Figueiredo C.A.V., Hartwig F.P., Horta B.L., Kehdy F.S.G., Lima-Costa M.F., Mauricio L. Barreto, Oliveira P.R.S., Pereira A.C., Ribeiro-Silva R.D.C., Rodrigues L.C., Tarazona-Santos E.M.Fuentes:scopusGenomic regions 10q22.2, 17q21.31, and 2p23.1 can contribute to a lower lung function in African descent populations
ArticleAbstract: Accumulated evidence supports the contribution of genetic factors in modulating airway function, espPalabras claves:Admixture mapping strategy, African ancestry, Lung function declineAutores:Araújo N.M., Cruz A.A., Figueiredo C.A.V., Fonseca H.F., Horta B.L., Lima N.P., Mauricio L. Barreto, Rios R., Santolalla M.L., Sant’Anna H.P., Saraiva M., Silva T.M., Tarazona-Santos E.M.Fuentes:scopus