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Aging Cell(1)
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Growth Hormone and IGF Research(1)
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Brain structure and function associated with younger adults in growth hormone receptor-deficient humans
ArticleAbstract: Growth hormone receptor deficiency (GHRD) results in short stature, enhanced insulin sensitivity, anPalabras claves:aging, COGNITION, Growth hormone receptor deficiency, IGF-1, Insulin, MRIAutores:Balasubramanian P., Braskie M.N., Enrique Terán, Guevara A., Hafzalla G.W., Jaime Guevara-Aguirre, Longo V.D., Mather M., Nashiro K., Nelson M.D., Thompson P.M., Velasco R., Wei M.Fuentes:googlescopusGH receptor deficiency in ecuadorian adults is associated with obesity and enhanced insulin sensitivity
Conference ObjectAbstract: Context: Ecuadorian subjects with GH receptor deficiency (GHRD) have not developed diabetes, despitePalabras claves:Autores:Alfaras I., Balasubramanian P., Carolina Guevara, De Cabo R., Di Biase S., Enrique Terán, Jaime Guevara-Aguirre, Longo V.D., Marco Guevara-Aguirre, Narvaez L., Procel P., Rosenbloom A.L., Saavedra J.Fuentes:googlescopusGrowth hormone receptor deficiency in humans associates to obesity, increased body fat percentage, a healthy brain and a coordinated insulin sensitivity
ArticleAbstract: Background: We have shown that subjects with Laron syndrome (LS) due to growth hormone receptor defiPalabras claves:BRAIN, Growth hormone receptor deficiency, Insulin-like growth factor binding protein 1, Laron syndrome, obesityAutores:Antonio Wenceslao Danilo Gavilanes, Carolina Guevara, Daniela Lescano, Enrique Terán, Guevara A., Jaime Guevara-Aguirre, Longo V.D.Fuentes:googlescopusGrowth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans
ArticleAbstract: Mutations in growth signaling pathways extend life span, as well as protect against age-dependent DNPalabras claves:Autores:Balasubramanian P., Cheng C.W., Cohen P., De Cabo R., Hwang D., Ingles S., Jaime Guevara-Aguirre, Longo V.D., Madia F., Marco Guevara-Aguirre, Martin-Montalvo A., Saavedra J., Wei M.Fuentes:scopusIGF-I regulates the age-dependent signaling peptide humanin
ArticleAbstract: Aging is influenced by endocrine pathways including the growth hormone/insulin-like growth factor-1Palabras claves:aging, Growth hormone, Humanin, IGF-I, longevityAutores:Bartke A., Cohen P., Fang Y., Jaime Guevara-Aguirre, Lee C., Longo V.D., Miyazaki B., Wan J., Yen K.Fuentes:scopusLow protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population
ArticleAbstract: Mice and humans with growth hormone receptor/IGF-1 deficiencies display major reductions in age-relaPalabras claves:Autores:Balasubramanian P., Brandhorst S., Cheng C.W., Cohen P., Crimmins E.M., Fontana L., Jaime Guevara-Aguirre, Kennedy B.K., Levine M.E., Longo V.D., Madia F., Mirisola M.G., Passarino G., Suarez J.A., Wan J., Wei M.Fuentes:scopus