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Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling
ArticleAbstract: The Ebola virus (EBOV) VP35 protein blocks the virus-induced phosphorylation and activation of interPalabras claves:Autores:Basler C.F., Gale M., Hartman A., Kimberlin C., Loo Y.M., Martínez-Sobrido L., Saphire E., Washington B. CárdenasFuentes:googlescopusEbola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKε and TBK-1
ArticleAbstract: The Ebola virus (EBOV) VP35 protein antagonizes the early antiviral alpha/beta interferon (IFN-α/β)Palabras claves:Autores:Basler C.F., Prins K.C., Washington B. CárdenasFuentes:googlescopusThe tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response
ArticleAbstract: On detecting viral RNAs, the RNA helicase retinoic acid-inducible gene I (RIG-I) activates the interPalabras claves:Autores:Basler C.F., Friedman C., Horvath C., Komuro A., Legarda-Addison D., Moran T., Ng A., O'Donnell M., Ting A., Washington B. Cárdenas, Xavier R., Yount J.Fuentes:googlescopus