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Hematogones with light chain restriction: A potential diagnostic pitfall when using flow cytometry analysis to assess bone marrow specimens
ArticleAbstract: Light-chain restricted hematogones (LCR HGs) detected by flow cytometry analysis can mimic bone marrPalabras claves:Daratumumab, Flow cytometry analysis, Hematogones, Light chain restricted hematogones, Lymphoma, MyelomaAutores:Challagundla P., El Hussein S., Fang H., Jorgensen J.L., Loghavi S., Lyapichev K.A., Medeiros L.J., Qiu L., Sofía A. Garcés, Tashakori M., Wang S.A., Wang W., Wang X.Fuentes:scopusFrom the archives of MD Anderson Cancer Center: Intravascular large B-cell lymphoma with numerous circulating lymphoma cells
ReviewAbstract: Intravascular large B-cell lymphoma (IVLBCL) is a rare, clinically aggressive form of large B-cell lPalabras claves:Bone marrow, Immunophenotype, Intravascular large B-cell lymphoma, Karyotype, Peripheral bloodAutores:Khoury J.D., Medeiros L.J., Qiu L., Sofía A. Garcés, Tang Z., Thakral B., Vega F., Wang S.A.Fuentes:scopusETNK1 mutation occurs in a wide spectrum of myeloid neoplasms and is not specific for atypical chronic myeloid leukemia
ArticleAbstract: Background: ETNK1 mutation has been suggested as a useful tool to support the diagnosis of atypicalPalabras claves:acute myeloid leukemia (AML), ethanolamine kinase 1 (ETNK1), myelodysplastic syndrome (MDS), myelodysplastic/myeloproliferative neoplasm (MDS/MPN), myeloproliferative neoplasm (MPN)Autores:Jabbour E.J., Jelloul F.Z., Li N., Li S., Medeiros L.J., Ok C.Y., Patel K.P., Rehder C., Shuai W., Sofía A. Garcés, Wang W., Xu J., Yin C.C., You M.J., Zuo Z.Fuentes:scopusConcurrent Mutations in SF3B1 and PHF6 in Myeloid Neoplasms
ArticleAbstract: It has been reported that gene mutations in SF3B1 and PHF6 are mutually exclusive. However, this obsPalabras claves:myeloid neoplasms, PHF6, SF3B1Autores:Chien K.S., Garcia-Manero G., Jelloul F.Z., Kanagal-Shamanna R., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Sofía A. Garcés, Yin C.C., Zuo Z.Fuentes:scopusCyclin D1 expression in Rosai-Dorfman disease: a near-constant finding that is not invariably associated with mitogen-activated protein kinase/extracellular signal–regulated kinase pathway activation
ArticleAbstract: Activating mutations in the mitogen-activated protein kinase/extracellular signal–regulated kinase (Palabras claves:BCL-2, Cyclin D1, Ki-67, MAPK/ERK, p-ERK, pathogenesis, Rosai-dorfman diseaseAutores:Bhattacharjee M.B., Coelho Siqueira S.A., Cuglievan B., Garces J.C., Jelloul F.Z., Khoury J.D., Li S., Marques-Piubelli M.L., Medeiros L.J., Medina A.M., Miranda R.N., Saluja K., Sofía A. Garcés, Sriganeshan V., Thakral B., Xu J., Yin C.C.Fuentes:scopusChronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype, and TP53 disruption
ArticleAbstract: The presence of expanded proliferation centers (PCs) in lymph nodes involved by chronic lymphocyticPalabras claves:Bone marrow, Chronic lymphocytic leukemia/small lymphocytic lymphoma, Complex karyotype, Proliferation centers, TP53Autores:Bueso-Ramos C., Hu S., Kanagal-Shamanna R., Khoury J.D., Loghavi S., Luthra R., Medeiros L.J., Ok C.Y., Patel K.P., Routbort M.J., Salem A., Schlette E., Sofía A. Garcés, Tang G., Wang S.A.Fuentes:scopusClassic Hodgkin lymphoma with marked granulomatous reaction: A clinicopathologic study of 20 cases
ArticleAbstract: Granulomatous reactions can be associated with various types of lymphoma, most commonly classic HodgPalabras claves:chronic granulomatous inflammation, Classic Hodgkin lymphoma, Epstein-Barr virus, JAK/STAT, Mixed cellularity, PD-L1Autores:Li S., Lin P., Medeiros L.J., Miranda R.N., Patel K.P., Sofía A. Garcés, Tang G., Tang Z., Wang W., Xu J., Yin C.C.Fuentes:scopusClinical, histopathologic, and immunoarchitectural features of dermatopathic lymphadenopathy: an update
ArticleAbstract: Dermatopathic lymphadenopathy is a distinctive form of paracortical lymph node hyperplasia that usuaPalabras claves:Autores:Castellano-Sánchez A., Garces J.C., Khoury J.D., Li S., Medeiros L.J., Medina A.M., Miranda R.N., Patel K.P., Poppiti R.J., Sofía A. Garcés, Sriganeshan V., Thakral B., Xu J., Yin C.C.Fuentes:scopusAcquired WT1 mutations contribute to relapse of NPM1-mutated acute myeloid leukemia following allogeneic hematopoietic stem cell transplant
ArticleAbstract: The role of WT1 protein in hematopoiesis and leukemogenesisis incompletely elucidated. WT1 overexprePalabras claves:Autores:DiNardo C.D., El Hussein S., Fang H., Furudate K., Kanagal-Shamanna R., Khoury J.D., Loghavi S., Lyapichev K.A., Medeiros L.J., Ok C.Y., Patel K.P., Ravandi F., Routbort M.J., Sofía A. Garcés, Takahashi K., Wang S.A.Fuentes:scopusFocal Rosai–Dorfman disease coexisting with lymphoma in the same anatomic site: a localized histiocytic proliferation associated with MAPK/ERK pathway activation
ArticleAbstract: Rosai–Dorfman disease is a rare histiocytic disorder shown to have gene mutations that activate thePalabras claves:Autores:González S., Johnson M.R., Khoury J.D., Li S., Manning J.T., Medeiros L.J., Molgó M., Patel K.P., Pina-Oviedo S., Ruiz-Cordero R., Sofía A. Garcés, Xu J., Yin C.C.Fuentes:scopus