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Early onset and long lasting protection in pigs provided by a classical swine fever E2-vaccine candidate produced in the milk of goats
ArticleAbstract: For vaccination against classical swine fever virus (CSFV), it is strongly desirable to induce a rapPalabras claves:CSFV, Duration of protection, E2 glycoprotein, Recombinant vaccinesAutores:Ávila M., Domínguez P., Farnos O., Frias M.T., Maritza Barrera, Rodriguez M.P., Sanchez O., Tait H., Toledo J.R., Vega E.Fuentes:scopusThermal stress treatment does not affect the stability and protective capacity of goat milk derived E2-marker vaccine formulation against CSFV
ArticleAbstract: Classical swine fever virus produces a huge mortality in infected herds during recurrent outbreaks,Palabras claves:E2-classical swine fever virus, Formulation stability, Mammary gland expression, Recombinant veterinary vaccineAutores:Aguero F., Aguilera A., Castell S., Farnos O., Figueredo J.M., Fonseca-Rodríguez O., Frias M.T., Maritza Barrera, Montesino R., Naranjo P., Prieto Y., Rodriguez M.P., Sanchez O., Toledo J.R.Fuentes:scopusA Novel Microencapsulated Bovine Recombinant Interferon Tau Formulation for Luteolysis Modulation in Cattle
ArticleAbstract: Early embryonic loss is a major cause of reproductive inefficiency in cattle, primarily due to premaPalabras claves:interferon tau, luteolysis modulation, MicroencapsulationAutores:Aleikar Vásquez, Camacho F., Felipe Sandoval, Florence Hugues, Garcia-Herreros M.G., Gutiérrez-Reinoso M.A., Ignacio Cabezas, Javiera Yáñez-Torres, Kelly Gancino, Lamazares E., Mena-Ulecia K., Paula Gädicke, Thelvia I. Ramos Gómez, Toledo J.R.Fuentes:scopusMultilayer Nanocarrier for the Codelivery of Interferons: A Promising Strategy for Biocompatible and Long-Acting Antiviral Treatment
ArticleAbstract: Background: Interferons (IFNs) are cytokines involved in the immune response with a synergistic reguPalabras claves:Antiproliferative, antiviral, Core-shell, Drug delivery system, Immunoregulation, interferons, nanoencapsulation, toxicityAutores:Altamirano C., Debut Alexis, Felipe Sandoval, Florence Hugues, Gómez-Gaete C., Hortensia Rodriguez Cabrera, Ignacio Cabezas, Lamazares E., Leandro Santiago-Padilla, marbel torres arias, Montesino R., Parra N.C., Ramos O.S., Santiago Nelson Vispo, Sarah Martin-Solano, Thelvia I. Ramos Gómez, Toledo J.R., Viana Manrique-Suárez, Villacis-Aguirre C.A.Fuentes:scopusEvaluating the adjuvant potential of NK-lysin and HMGB1-derived peptides in enhancing immune responses in Salmo salar
ArticleAbstract: The development of effective vaccines for aquaculture is crucial to prevent infectious diseases andPalabras claves:adjuvant, Antimicrobial peptide, HMGB1, NK-Lysin, Salmo salarAutores:Acosta J., Alex Romero, Alfredo Saavedra, Bastian Couso, Carolina Muñoz-Flores, Crisleri Carrera, Fátima Reyes, Jorge Saavedra, Leonardo Ortega, Milton F. Villegas, Montesino R., Niza Agurto, Parra N.C., Rafael Maura, S. Salazar, Sanchez O., Toledo J.R., Valenzuela A.Fuentes:scopusNew insight into the biological activity of Salmo salar NK-lysin antimicrobial peptides
ArticleAbstract: NK-lysin is a potent antimicrobial peptide (AMP) with antimicrobial activity against bacteria, fungiPalabras claves:Antimicrobial peptide, cytokines, Immune response, NK-Lysin, Salmo salarAutores:Acosta J., Alex Romero, Astuya-Villalón A., Carolina Muñoz-Flores, Crisleri Carrera, Ercilia T. Pérez, Fátima Reyes, Lamazares E., Leonardo Ortega, María F. Starck, Milton F. Villegas, Montesino R., Natacha Santibáñez, Niza Agurto, Pamela Ruíz, Parra N.C., S. Salazar, Sanchez O., Toledo J.R., Valenzuela A.Fuentes:scopusNew Formulation of a Subunit Vaccine Candidate against Lawsonia intracellularis Increases Humoral and Cellular Immune Responses
ArticleAbstract: Previously, we designed a subunit vaccine candidate based on three L. intracellularis antigens withPalabras claves:ISA 660 VG, LAWSONIA INTRACELLULARIS, pig immune response, Subunit vaccine, water-in-oil formulationAutores:Acosta J., Estefanía Nova-Lamperti, González A., María F. Starck, Milton F. Villegas, Montesino R., Paula Gädicke, Ramos E., Ruiz A., S. Salazar, Sanchez O., Toledo J.R.Fuentes:scopusThe Hitchhiker’s Guide to Human Therapeutic Nanoparticle Development
ReviewAbstract: Nanomedicine plays an essential role in developing new therapies through novel drug delivery systemsPalabras claves:clinical trials, Immunotoxicity, nanomedicine, Nanoparticles, pharmacokinetics, Preclinical, Regulatory aspectsAutores:Altamirano C., Katherine V. López-Aguilar, Santiago Nelson Vispo, Thelvia I. Ramos Gómez, Toledo J.R., Villacis-Aguirre C.A.Fuentes:scopusEffectiveness of the E2-classical swine fever virus recombinant vaccine produced and formulated within whey from genetically transformed goats
ArticleAbstract: Subunit recombinant vaccines against classical swine fever virus (CSFV) are a promising alternativePalabras claves:Autores:Cortez-San Martín M., Farnos O., Maritza Barrera, Meza C.D., Parra N.C., Rivas C.I., Saavedra P.A., Salgado E.R., Sanchez O., Toledo J.R.Fuentes:scopusEstablishment of a production process for a novel vaccine candidate against Lawsonia intracellularis
ArticleAbstract: Background: Lawsonia intracellularis remains a problem for the swine industry worldwide. Previously,Palabras claves:fed-batch culture, Immune response, LAWSONIA INTRACELLULARIS, Proliferative enteropathy, Recombinant vaccineAutores:Acosta J., Altamirano C., González A., Gutiérrez N., Montesino R., Ramos E., S. Salazar, Sanchez O., Thelvia I. Ramos Gómez, Toledo J.R.Fuentes:scopus