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Article(6)
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Biochimica et Biophysica Acta - General Subjects(1)
Chemical Communications(1)
Chemistry and Physics of Lipids(1)
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Journal of the American Chemical Society(1)
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Fisiología humana(5)
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scopus(6)
3-Ketosphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells
ArticleAbstract: Although several reports describe the metabolic fate of sphingoid bases and their analogs, as well aPalabras claves:Autores:Abad J.L., Bedia C., Casas J., Delgado A., Fabrias G., González J., Yadira F. OrdóñezFuentes:scopusActivity-Based Imaging of Acid Ceramidase in Living Cells
ArticleAbstract: Acid ceramidase (AC) hydrolyzes ceramides into sphingoid bases and fatty acids. The enzyme is overexPalabras claves:Autores:Abad J.L., Aseeri M., Casas J., Casasampere M., Delgado A., Fabrias G., Garcia V., Levade T., Schuchman E.H., Triola G., Yadira F. OrdóñezFuentes:scopusFrom the configurational preference of dihydroceramide desaturase-1 towards Δ<sup>6</sup>-unsaturated substrates to the discovery of a new inhibitor
ArticleAbstract: Dihydroceramide desaturase 1 (Des1) catalyzes the last step of ceramide synthesis de novo, thus reguPalabras claves:Autores:Abad J.L., Casas J., Delgado A., Fabrias G., Garrido M., Pou A., Yadira F. OrdóñezFuentes:scopusDihydroceramide desaturase inhibitors induce autophagy via dihydroceramide-dependent and independent mechanisms
ArticleAbstract: Background Autophagy consists on the delivery of cytoplasmic material and organelles to lysosomes foPalabras claves:Autophagy, Cáncer, Dihydroceramide desaturase, inhibitor, lipidomics, SphingolipidsAutores:Casas J., Casasampere M., Fabrias G., Yadira F. OrdóñezFuentes:scopusInhibitors of dihydroceramide desaturase 1: Therapeutic agents and pharmacological tools to decipher the role of dihydroceramides in cell biology
ArticleAbstract: Dihydroceramide desaturase (Des1) is the last enzyme in the de novo synthesis of ceramides (Cer). ItPalabras claves:Autophagy, Ceramides, Fenretinide, ResveratrolAutores:Casas J., Casasampere M., Pou A., Yadira F. OrdóñezFuentes:scopusLiver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
ArticleAbstract: The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the globPalabras claves:AAV, CPT1A, fatty-acid oxidation, Gene therapy, hepatic steatosis, lipid biomarker, obesityAutores:Alonso S., Bartrons R., Calderón-Domínguez M., Casals N., Casas J., Escolà-Gil J.C., Frühbeck G., Fucho R., Herrero L., Llorente-Cortes V., Mera P., Mir J.F., Montironi C., Rodríguez A., Salvador J., Sánchez-Infantes D., Sandra Recalde, Sebastián D., Serra D., Soler-Vázquez M.C., Valentí V., Weber M., Zorzano A.Fuentes:scopus