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From the configurational preference of dihydroceramide desaturase-1 towards Δ<sup>6</sup>-unsaturated substrates to the discovery of a new inhibitor
ArticleAbstract: Dihydroceramide desaturase 1 (Des1) catalyzes the last step of ceramide synthesis de novo, thus reguPalabras claves:Autores:Abad J.L., Casas J., Delgado A., Fabrias G., Garrido M., Pou A., Yadira F. OrdóñezFuentes:scopusInhibitors of dihydroceramide desaturase 1: Therapeutic agents and pharmacological tools to decipher the role of dihydroceramides in cell biology
ArticleAbstract: Dihydroceramide desaturase (Des1) is the last enzyme in the de novo synthesis of ceramides (Cer). ItPalabras claves:Autophagy, Ceramides, Fenretinide, ResveratrolAutores:Casas J., Casasampere M., Pou A., Yadira F. OrdóñezFuentes:scopusLiver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
ArticleAbstract: The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased drastically due to the globPalabras claves:AAV, CPT1A, fatty-acid oxidation, Gene therapy, hepatic steatosis, lipid biomarker, obesityAutores:Alonso S., Bartrons R., Calderón-Domínguez M., Casals N., Casas J., Escolà-Gil J.C., Frühbeck G., Fucho R., Herrero L., Llorente-Cortes V., Mera P., Mir J.F., Montironi C., Rodríguez A., Salvador J., Sánchez-Infantes D., Sandra Recalde, Sebastián D., Serra D., Soler-Vázquez M.C., Valentí V., Weber M., Zorzano A.Fuentes:scopus