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Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway
ArticleAbstract: Physical exercise has been shown to exert antidepressant effects, but the mechanisms underlying thisPalabras claves:Antidepressant, FNDC5, Irisin, neurogenesis, physical exerciseAutores:Aline Siteneski, Brocardo P.S., Camargo A., Cunha M.P., Fraga D.B., Gil-Mohapel J., Olescowicz G., Pazini F.L., Rodrigues A.L.S.Fuentes:googlescopusA low-dose combination of ketamine and guanosine counteracts corticosterone-induced depressive-like behavior and hippocampal synaptic impairments via mTORC1 signaling
ArticleAbstract: Ketamine exhibits rapid and sustained antidepressant responses, but its repeated use may cause adverPalabras claves:Augmentation strategy, Corticosterone, Depression, Guanosine, KetamineAutores:Aline Siteneski, Camargo A., Dalmagro A.P., Rodrigues A.L.S., Wolin I.A.V., Zeni A.L.B.Fuentes:googlescopusCentral irisin administration affords antidepressant-like effect and modulates neuroplasticity-related genes in the hippocampus and prefrontal cortex of mice
ArticleAbstract: Evidence has indicated that the practice of physical exercise has antidepressant effects that mightPalabras claves:Antidepressant, BDNF, FNDC5, Irisin, PGC-1αAutores:Aline Siteneski, Brocardo P.S., Cunha M.P., Gruhn K., Lieberknecht V., Pazini F.L., Rodrigues A.L.S.Fuentes:googlescopus