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High frequency and founder effect of the CYP3A4∗20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme
ArticleAbstract: Cytochrome P450 3A4 (CYP3A4) is a key drug-metabolizing enzyme. Loss-of-function variants have beenPalabras claves:Autores:Adrián LLerena, Apellániz-Ruiz M., Carracedo Á., Cascón A., Comino-Méndez I., Currás-Freixes M., De Cubas A.A., Grazina M., Ingelman-Sundberg M., Inglada-Pérez L., Mancikova V., Moya G.E., Naranjo M.E.G., Opocher G., Rasool M., Rebai A., Robledo M., Rodríguez-Antona C., Sánchez L., Taboada-Echalar P., Triki S.Fuentes:scopusPharmacogenomic information in drug labels: European Medicines Agency perspective
ReviewAbstract: Pharmacogenomics (PGx) has a growing impact on healthcare and constitutes one of the major pillars oPalabras claves:Autores:Adrián LLerena, Caneva L., Ehmann F., Ingelman-Sundberg M., Maliepaard M., Papaluca-Amati M., Paulmichl M., Prasad K.Fuentes:scopusThe Sixth European Society of Pharmacogenomics and Personalised Therapy Congress
Conference ObjectAbstract: On 8-9 November 2022, the European Society of Pharmacogenomics and Personalised Therapy organized itPalabras claves:Autores:Adrián LLerena, Akin D., Ansari M., Bozina N., Christrup L., Daly A.K., Florindi F., Henricks L.M., Ingelman-Sundberg M., Manolopoulos V.G., Molden E., Morris T., Muller D.J., Niemi M., Patrinos G.P., Pavlovic S., Primorac D., Russmann S., Sipeky C., Stanković S., Swen J.J., Van Den Broek W., Van Schaik R.H.N., Zukic B.Fuentes:scopus