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FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer
ArticleAbstract: MicroRNAs are small RNAs that negatively regulate gene expression posttranscriptionally. Because chaPalabras claves:Autores:Esteban A. Orellana, Kasinski A.L., Low P.S., Lyle L.T., Rangasamy L., Tenneti S.Fuentes:scopusEnhancing MicroRNA Activity through Increased Endosomal Release Mediated by Nigericin
ArticleAbstract: The therapeutic promise of small-RNA therapeutics is limited, not only by the lack of delivery vehicPalabras claves:DELIVERY, endosomal escape, folate, folate-conjugates, ligand, microRNA, miR-34, nigericinAutores:Abdelaal A.M., Esteban A. Orellana, Kasinski A.L., Low P.S., Myoung S., Rangasamy L., Tenneti S.Fuentes:scopusNew Mechanism for Release of Endosomal Contents: Osmotic Lysis via Nigericin-Mediated K<sup>+</sup>/H<sup>+</sup> Exchange
ArticleAbstract: Although peptides, antibodies/antibody fragments, siRNAs, antisense DNAs, enzymes, and aptamers arePalabras claves:Autores:Bandara N.A., Chelvam V., Esteban A. Orellana, Kanduluru A.K., Kasinski A.L., Low P.S., Rangasamy L., Srinivasarao M., You F.Fuentes:scopus