Prioritizing hits with appropriate trade-offs between HIV-1 reverse transcriptase inhibitory efficacy and MT4 blood cells toxicity through desirability-based multiobjective optimization and ranking

Article

Abstract: Nonnucleoside reverse transcriptase (RT) inhibitors (NNRTIs) constitute a promising therapeutic opti

Palabras claves:

Drug Discovery, HIV-1, Multiobjective optimization, NNRTI, Virtual Screening

Autores:

Borges F., Maykel Cruz-Monteagudo, Natalia Dias Soeiro Cordeiro M., The H.

Fuentes:

scopus