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Article(2)
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Clinical and biochemical consequences of CYP17A1 inhibition with abiraterone given with and without exogenous glucocorticoids in castrate men with advanced prostate cancer
ArticleAbstract: Context: Abiraterone acetate is a small-molecule cytochrome P450 17A1 (CYP17A1) inhibitor that is acPalabras claves:Autores:Arlt W., Attard G., Cassidy A.M., De Bono J.S., Dowsett M., Folkerd E., Hughes B.A., Oommen N.B., Reid A.H.M., Richard J. Auchus, Thompson E.Fuentes:scopusImpaired 17,20-lyase activity in male mice lacking cytochrome b<inf>5</inf> in leydig cells
ArticleAbstract: Androgen and estrogen biosynthesis in mammals requires the 17,20-lyase activity of cytochrome P450 1Palabras claves:Autores:Arlt W., Chomic R., Hughes B.A., Kliewer S.A., Liu J., Mangelsdorf D.J., Owen B.M., Richard J. Auchus, Sondhi V.Fuentes:scopus