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11-Oxygenated androgens are biomarkers of adrenal volume and testicular adrenal rest tumors in 21-hydroxylase deficiency
ArticleAbstract: Context: Patients with 21-hydroxylase deficiency (21OHD) have long-term complications, resulting froPalabras claves:Autores:Avila N.A., Elman M.S., Mallappa A., Marko J., Merke D.P., Rao H., Richard J. Auchus, Tsodikov A., Turcu A.F.Fuentes:scopusA Phase 2, Multicenter Study of Nevanimibe for the Treatment of Congenital Adrenal Hyperplasia
ArticleAbstract: Context: Patients with classic congenital adrenal hyperplasia (CAH) often require supraphysiologic gPalabras claves:adrenal hypertrophy, ATR-101, Clinical trial, Congenital adrenal hyperplasia, nevanimibeAutores:Chang A.Y., El-Maouche D., Joyal E.G., Lin V.H., Merke D.P., Mohideen P., Plaunt M.R., Richard J. Auchus, Turcu A.F., Vogiatzi M.G., Weintraub L.Fuentes:scopusCongenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management
ReviewAbstract: Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting cortisolPalabras claves:21-hydroxylase deficiency, aldosterone, cortisol, CYP21A2, Glucocorticoid, mineralocorticoid, Steroid biosynthesisAutores:Arlt W., Faisal Ahmed S., Falhammar H., Flück C.E., Guasti L., Huebner A., Kortmann B.B.M., Krone N., Merke D.P., Miller W.L., Nordenström A., Reisch N., Richard J. Auchus, Sandberg D.E., Speiser P.W., Stikkelbroeck N.M.M.L., Touraine P., Utari A., van der Grinten H.L.C., White P.C., Wudy S.A.Fuentes:scopusCorrection to: Tildacerfont in Adults With Classic Congenital Adrenal Hyperplasia: Results from Two Phase 2 Studies (The Journal of Clinical Endocrinology and Metabolism (2021) 106:11 (e4666-e4679) DOI: 10.1210/clinem/dgab438)
OtherAbstract: Table 2 contained an error in the listed dose. For cohort B, the dose was incorrectly listed as 200Palabras claves:Autores:Barnes C.N., Huang M., Imel E.A., Madu I.J., Merke D.P., Moriarty D., Nakhle S., Newfield R.S., Richard J. Auchus, Sarafoglou K., Vogiatzi M.G.Fuentes:scopusTildacerfont in Adults with Classic Congenital Adrenal Hyperplasia: Results from Two Phase 2 Studies
ArticleAbstract: Context: Congenital adrenal hyperplasia due to 21-hydroxylase deficiency (21OHD) is typically treatePalabras claves:17-hydroxyprogesterone, adrenocorticotropic hormone, androstenedione, Congenital adrenal hyperplasia, CRF-receptor antagonist, tildacerfontAutores:Barnes C.N., Huang M., Imel E.A., Madu I.J., Merke D.P., Moriarty D., Nakhle S., Newfield R.S., Richard J. Auchus, Sarafoglou K., Vogiatzi M.G.Fuentes:scopus